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B7‐33, a Functionally Selective Relaxin Receptor 1 Agonist, Attenuates Myocardial Infarction–Related Adverse Cardiac Remodeling in Mice

BACKGROUND: Human relaxin‐2 is a peptide hormone capable of pleiotropic effects in several organ systems. Its recombinant formulation (serelaxin) has been demonstrated to reduce infarct size and prevent excessive scar formation in animal models of cardiac ischemia‐reperfusion injury. B7‐33, a synthe...

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Detalles Bibliográficos
Autores principales: Devarakonda, Teja, Mauro, Adolfo G., Guzman, Geronimo, Hovsepian, Sahak, Cain, Chad, Das, Anindita, Praveen, Praveen, Hossain, Mohammed Akhter, Salloum, Fadi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428518/
https://www.ncbi.nlm.nih.gov/pubmed/32295457
http://dx.doi.org/10.1161/JAHA.119.015748

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