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Increased Myocardial Oxygen Consumption Precedes Contractile Dysfunction in Hypertrophic Cardiomyopathy Caused by Pathogenic TNNT2 Gene Variants

BACKGROUND: Hypertrophic cardiomyopathy is caused by pathogenic sarcomere gene variants. Individuals with a thin‐filament variant present with milder hypertrophy than carriers of thick‐filament variants, although prognosis is poorer. Herein, we defined if decreased energetic status of the heart is a...

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Detalles Bibliográficos
Autores principales:	Parbhudayal, Rahana Y., Harms, Hendrik J., Michels, Michelle, van Rossum, Albert C., Germans, Tjeerd, van der Velden, Jolanda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428531/ https://www.ncbi.nlm.nih.gov/pubmed/32290750 http://dx.doi.org/10.1161/JAHA.119.015316

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