Cargando…

Multidisciplinary Heart Team Approach for Complex Coronary Artery Disease: Single Center Clinical Presentation

BACKGROUND: The Heart Team approach is ascribed a Class I recommendation in contemporary guidelines for revascularization of complex coronary artery disease. However, limited data are available regarding the decision‐making and outcomes of patients based on this strategy. METHODS AND RESULTS: One hu...

Descripción completa

Detalles Bibliográficos
Autores principales: Young, Michael N., Kolte, Dhaval, Cadigan, Mary E., Laikhter, Elizabeth, Sinclair, Kevin, Pomerantsev, Eugene, Fifer, Michael A., Sundt, Thoralf M., Yeh, Robert W., Jaffer, Farouc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428540/
https://www.ncbi.nlm.nih.gov/pubmed/32308096
http://dx.doi.org/10.1161/JAHA.119.014738
_version_ 1783571095952031744
author Young, Michael N.
Kolte, Dhaval
Cadigan, Mary E.
Laikhter, Elizabeth
Sinclair, Kevin
Pomerantsev, Eugene
Fifer, Michael A.
Sundt, Thoralf M.
Yeh, Robert W.
Jaffer, Farouc A.
author_facet Young, Michael N.
Kolte, Dhaval
Cadigan, Mary E.
Laikhter, Elizabeth
Sinclair, Kevin
Pomerantsev, Eugene
Fifer, Michael A.
Sundt, Thoralf M.
Yeh, Robert W.
Jaffer, Farouc A.
author_sort Young, Michael N.
collection PubMed
description BACKGROUND: The Heart Team approach is ascribed a Class I recommendation in contemporary guidelines for revascularization of complex coronary artery disease. However, limited data are available regarding the decision‐making and outcomes of patients based on this strategy. METHODS AND RESULTS: One hundred sixty‐six high‐risk coronary artery disease patients underwent Heart Team evaluation at a single institution between January 2015 and November 2018. We prospectively collected data on demographics, symptoms, Society of Thoracic Surgeons Predicted Risk of Mortality/Synergy Between PCI with Taxus and Cardiac Surgery (STS‐PROM/SYNTAX) scores, mode of revascularization, and outcomes. Mean age was 70.0 years; 122 (73.5%) patients were male. Prevalent comorbidities included diabetes mellitus (51.8%), peripheral artery disease (38.6%), atrial fibrillation (27.1%), end‐stage renal disease on dialysis (13.3%), and chronic obstructive pulmonary disease (21.7%). Eighty‐seven (52.4%) patients had New York Heart Association III‐IV and 112 (67.5%) had Canadian Cardiovascular Society III‐IV symptomatology. Sixty‐seven (40.4%) patients had left main and 118 (71.1%) had 3‐vessel coronary artery disease. The median STS‐PROM was 3.6% (interquartile range 1.9, 8.0) and SYNTAX score was 26 (interquartile range 20, 34). The median number of physicians per Heart Team meeting was 6 (interquartile range 5, 8). Seventy‐nine (47.6%) and 49 (29.5%) patients underwent percutaneous coronary intervention and coronary artery bypass grafting, respectively. With increasing STS‐PROM (low, intermediate, high operative risk), coronary artery bypass graft was performed less often (47.9%, 18.5%, 15.2%) and optimal medical therapy was recommended more often (11.3%, 18.5%, 30.3%). There were no trends in recommendation for coronary artery bypass graft, percutaneous coronary intervention, or optimal medical therapy by SYNTAX score tertiles. In‐hospital and 30‐day mortality was 3.9% and 4.8%, respectively. CONCLUSIONS: Integrating a multidisciplinary Heart Team into institutional practice is feasible and provides a formalized approach to evaluating complex coronary artery disease patients. The comprehensive assessment of surgical, anatomical, and other risk scores using a decision aid may guide appropriate, evidence‐based management within this team‐based construct.
format Online
Article
Text
id pubmed-7428540
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-74285402020-08-17 Multidisciplinary Heart Team Approach for Complex Coronary Artery Disease: Single Center Clinical Presentation Young, Michael N. Kolte, Dhaval Cadigan, Mary E. Laikhter, Elizabeth Sinclair, Kevin Pomerantsev, Eugene Fifer, Michael A. Sundt, Thoralf M. Yeh, Robert W. Jaffer, Farouc A. J Am Heart Assoc Original Research BACKGROUND: The Heart Team approach is ascribed a Class I recommendation in contemporary guidelines for revascularization of complex coronary artery disease. However, limited data are available regarding the decision‐making and outcomes of patients based on this strategy. METHODS AND RESULTS: One hundred sixty‐six high‐risk coronary artery disease patients underwent Heart Team evaluation at a single institution between January 2015 and November 2018. We prospectively collected data on demographics, symptoms, Society of Thoracic Surgeons Predicted Risk of Mortality/Synergy Between PCI with Taxus and Cardiac Surgery (STS‐PROM/SYNTAX) scores, mode of revascularization, and outcomes. Mean age was 70.0 years; 122 (73.5%) patients were male. Prevalent comorbidities included diabetes mellitus (51.8%), peripheral artery disease (38.6%), atrial fibrillation (27.1%), end‐stage renal disease on dialysis (13.3%), and chronic obstructive pulmonary disease (21.7%). Eighty‐seven (52.4%) patients had New York Heart Association III‐IV and 112 (67.5%) had Canadian Cardiovascular Society III‐IV symptomatology. Sixty‐seven (40.4%) patients had left main and 118 (71.1%) had 3‐vessel coronary artery disease. The median STS‐PROM was 3.6% (interquartile range 1.9, 8.0) and SYNTAX score was 26 (interquartile range 20, 34). The median number of physicians per Heart Team meeting was 6 (interquartile range 5, 8). Seventy‐nine (47.6%) and 49 (29.5%) patients underwent percutaneous coronary intervention and coronary artery bypass grafting, respectively. With increasing STS‐PROM (low, intermediate, high operative risk), coronary artery bypass graft was performed less often (47.9%, 18.5%, 15.2%) and optimal medical therapy was recommended more often (11.3%, 18.5%, 30.3%). There were no trends in recommendation for coronary artery bypass graft, percutaneous coronary intervention, or optimal medical therapy by SYNTAX score tertiles. In‐hospital and 30‐day mortality was 3.9% and 4.8%, respectively. CONCLUSIONS: Integrating a multidisciplinary Heart Team into institutional practice is feasible and provides a formalized approach to evaluating complex coronary artery disease patients. The comprehensive assessment of surgical, anatomical, and other risk scores using a decision aid may guide appropriate, evidence‐based management within this team‐based construct. John Wiley and Sons Inc. 2020-04-20 /pmc/articles/PMC7428540/ /pubmed/32308096 http://dx.doi.org/10.1161/JAHA.119.014738 Text en © 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Young, Michael N.
Kolte, Dhaval
Cadigan, Mary E.
Laikhter, Elizabeth
Sinclair, Kevin
Pomerantsev, Eugene
Fifer, Michael A.
Sundt, Thoralf M.
Yeh, Robert W.
Jaffer, Farouc A.
Multidisciplinary Heart Team Approach for Complex Coronary Artery Disease: Single Center Clinical Presentation
title Multidisciplinary Heart Team Approach for Complex Coronary Artery Disease: Single Center Clinical Presentation
title_full Multidisciplinary Heart Team Approach for Complex Coronary Artery Disease: Single Center Clinical Presentation
title_fullStr Multidisciplinary Heart Team Approach for Complex Coronary Artery Disease: Single Center Clinical Presentation
title_full_unstemmed Multidisciplinary Heart Team Approach for Complex Coronary Artery Disease: Single Center Clinical Presentation
title_short Multidisciplinary Heart Team Approach for Complex Coronary Artery Disease: Single Center Clinical Presentation
title_sort multidisciplinary heart team approach for complex coronary artery disease: single center clinical presentation
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428540/
https://www.ncbi.nlm.nih.gov/pubmed/32308096
http://dx.doi.org/10.1161/JAHA.119.014738
work_keys_str_mv AT youngmichaeln multidisciplinaryheartteamapproachforcomplexcoronaryarterydiseasesinglecenterclinicalpresentation
AT koltedhaval multidisciplinaryheartteamapproachforcomplexcoronaryarterydiseasesinglecenterclinicalpresentation
AT cadiganmarye multidisciplinaryheartteamapproachforcomplexcoronaryarterydiseasesinglecenterclinicalpresentation
AT laikhterelizabeth multidisciplinaryheartteamapproachforcomplexcoronaryarterydiseasesinglecenterclinicalpresentation
AT sinclairkevin multidisciplinaryheartteamapproachforcomplexcoronaryarterydiseasesinglecenterclinicalpresentation
AT pomerantseveugene multidisciplinaryheartteamapproachforcomplexcoronaryarterydiseasesinglecenterclinicalpresentation
AT fifermichaela multidisciplinaryheartteamapproachforcomplexcoronaryarterydiseasesinglecenterclinicalpresentation
AT sundtthoralfm multidisciplinaryheartteamapproachforcomplexcoronaryarterydiseasesinglecenterclinicalpresentation
AT yehrobertw multidisciplinaryheartteamapproachforcomplexcoronaryarterydiseasesinglecenterclinicalpresentation
AT jafferfarouca multidisciplinaryheartteamapproachforcomplexcoronaryarterydiseasesinglecenterclinicalpresentation