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Smad3 Regulates Neuropilin 2 Transcription by Binding to its 5′ Untranslated Region

BACKGROUND: Vascular smooth muscle cell phenotypic change and consequential intimal hyperplasia (IH) cause arterial stenosis and posttreatment restenosis. Smad3 is a master transcription factor, yet its underlying functional mechanisms in this disease context are not well defined. METHODS AND RESULT...

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Detalles Bibliográficos
Autores principales: Xie, Xiujie, Urabe, Go, Marcho, Lynn, Williams, Corey, Guo, Lian‐Wang, Kent, K. Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428547/
https://www.ncbi.nlm.nih.gov/pubmed/32306814
http://dx.doi.org/10.1161/JAHA.119.015487