Oxygen Exposure During Cardiopulmonary Resuscitation Is Associated With Cerebral Oxidative Injury in a Randomized, Blinded, Controlled, Preclinical Trial

BACKGROUND: Hyperoxia during cardiopulmonary resuscitation (CPR) may lead to oxidative injury from mitochondrial‐derived reactive oxygen species, despite guidelines recommending 1.0 inspired oxygen during CPR. We hypothesized exposure to 1.0 inspired oxygen during CPR would result in cerebral hypero...

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Detalles Bibliográficos
Autores principales: Marquez, Alexandra M., Morgan, Ryan W., Ko, Tiffany, Landis, William P., Hefti, Marco M., Mavroudis, Constantine D., McManus, Meagan J., Karlsson, Michael, Starr, Jonathan, Roberts, Anna L., Lin, Yuxi, Nadkarni, Vinay, Licht, Daniel J., Berg, Robert A., Sutton, Robert M., Kilbaugh, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428577/
https://www.ncbi.nlm.nih.gov/pubmed/32321350
http://dx.doi.org/10.1161/JAHA.119.015032

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