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Associations of Peripheral Artery Disease With Calf Skeletal Muscle Mitochondrial DNA Heteroplasmy
BACKGROUND: Patients with peripheral artery disease (PAD) undergo frequent episodes of ischemia‐reperfusion in lower extremity muscles that may negatively affect mitochondrial health and are associated with impaired mobility. We hypothesized that skeletal muscle from PAD patients will show high mito...
Autores principales: | Gonzalez‐Freire, Marta, Moore, A. Zenobia, Peterson, Charlotte A., Kosmac, Kate, McDermott, Mary M., Sufit, Robert L., Guralnik, Jack M., Polonsky, Tamar, Tian, Lu, Kibbe, Melina R., Criqui, Michael H., Li, Lingyu, Leeuwenburgh, Christian, Ferrucci, Luigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428597/ https://www.ncbi.nlm.nih.gov/pubmed/32200714 http://dx.doi.org/10.1161/JAHA.119.015197 |
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