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PCSK9 Protein and rs562556 Polymorphism Are Associated With Arterial Plaques in Healthy Middle‐Aged Population: The STANISLAS Cohort
BACKGROUND: PCSK9 (Proprotein convertase subtilisin/kexin type 9) binds low‐density lipoprotein receptor, preventing its recycling. PCSK9 is a risk predictor and a biotarget in atherosclerosis. The PCSK9‐rs562556 variant has been reported as a gain‐of‐function mutation. The aim of this study was to...
Autores principales: | Ferreira, João Pedro, Xhaard, Constance, Lamiral, Zohra, Borges‐Canha, Marta, Neves, João Sérgio, Dandine‐Roulland, Claire, LeFloch, Edith, Deleuze, Jean‐François, Bacq‐Daian, Delphine, Bozec, Erwan, Girerd, Nicolas, Boivin, Jean‐Marc, Zannad, Faiez, Rossignol, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428603/ https://www.ncbi.nlm.nih.gov/pubmed/32208829 http://dx.doi.org/10.1161/JAHA.119.014758 |
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