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Impact of the Commercial Introduction of Transcatheter Mitral Valve Repair on Mitral Surgical Practice

BACKGROUND: There has been uncertainty regarding the effect of transcatheter mitral valve repair (TMVr) with MitraClip on cardiac surgical practice. Our aim was to examine the impact of the commercial introduction of TMVr to a comprehensive mitral program. METHODS AND RESULTS: We evaluated 875 patie...

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Autores principales: Niikura, Hiroki, Gössl, Mario, Bae, Richard, Sun, Benjamin, Askew, Judah, Harris, Kevin, Mudy, Karol, Strauss, Craig, Stanberry, Larissa, Sweeney, Andrea, Sorajja, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428655/
https://www.ncbi.nlm.nih.gov/pubmed/32248763
http://dx.doi.org/10.1161/JAHA.119.014874
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author Niikura, Hiroki
Gössl, Mario
Bae, Richard
Sun, Benjamin
Askew, Judah
Harris, Kevin
Mudy, Karol
Strauss, Craig
Stanberry, Larissa
Sweeney, Andrea
Sorajja, Paul
author_facet Niikura, Hiroki
Gössl, Mario
Bae, Richard
Sun, Benjamin
Askew, Judah
Harris, Kevin
Mudy, Karol
Strauss, Craig
Stanberry, Larissa
Sweeney, Andrea
Sorajja, Paul
author_sort Niikura, Hiroki
collection PubMed
description BACKGROUND: There has been uncertainty regarding the effect of transcatheter mitral valve repair (TMVr) with MitraClip on cardiac surgical practice. Our aim was to examine the impact of the commercial introduction of TMVr to a comprehensive mitral program. METHODS AND RESULTS: We evaluated 875 patients (aged 69±14 years; 58% men) who underwent transcatheter or mitral surgical procedures over a 6‐year period at our institution. Main outcomes were changes in surgical procedural volume after TMVr introduction and short‐term mortality for surgical and TMVr procedures. The numbers of patients treated with MitraClip, isolated mitral repair, and any mitral surgery were 249, 292, and 626 patients, respectively. Compared with surgery, patients with MitraClip were older (aged 82±8 versus 64±12 years; P<0.001) and had more severe morbidity. Following the introduction of MitraClip, surgical volumes steadily increased to a rate of 10 (95% CI, 3–7) procedures per year for isolated mitral procedures and 17 (95% CI, 13–20) procedures per year for all mitral surgeries. Both MitraClip and surgical volumes increased at the same rate (P=0.42). In‐hospital mortality was 3.2% for MitraClip and 2.1% for all mitral surgeries (P=0.33). At 30 days, survival free of all mortality (P=0.17) and freedom from heart failure rehospitalization (P=0.75) were similar for transcatheter and surgical procedures. CONCLUSIONS: The commercial introduction of TMVr may be associated with growth in cardiac surgery, without detracting from other therapies, and favorable clinical outcomes for all treated mitral regurgitation patients. These findings demonstrate the potential benefits of complementary therapies in the treatment of patients with mitral regurgitation.
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spelling pubmed-74286552020-08-17 Impact of the Commercial Introduction of Transcatheter Mitral Valve Repair on Mitral Surgical Practice Niikura, Hiroki Gössl, Mario Bae, Richard Sun, Benjamin Askew, Judah Harris, Kevin Mudy, Karol Strauss, Craig Stanberry, Larissa Sweeney, Andrea Sorajja, Paul J Am Heart Assoc Original Research BACKGROUND: There has been uncertainty regarding the effect of transcatheter mitral valve repair (TMVr) with MitraClip on cardiac surgical practice. Our aim was to examine the impact of the commercial introduction of TMVr to a comprehensive mitral program. METHODS AND RESULTS: We evaluated 875 patients (aged 69±14 years; 58% men) who underwent transcatheter or mitral surgical procedures over a 6‐year period at our institution. Main outcomes were changes in surgical procedural volume after TMVr introduction and short‐term mortality for surgical and TMVr procedures. The numbers of patients treated with MitraClip, isolated mitral repair, and any mitral surgery were 249, 292, and 626 patients, respectively. Compared with surgery, patients with MitraClip were older (aged 82±8 versus 64±12 years; P<0.001) and had more severe morbidity. Following the introduction of MitraClip, surgical volumes steadily increased to a rate of 10 (95% CI, 3–7) procedures per year for isolated mitral procedures and 17 (95% CI, 13–20) procedures per year for all mitral surgeries. Both MitraClip and surgical volumes increased at the same rate (P=0.42). In‐hospital mortality was 3.2% for MitraClip and 2.1% for all mitral surgeries (P=0.33). At 30 days, survival free of all mortality (P=0.17) and freedom from heart failure rehospitalization (P=0.75) were similar for transcatheter and surgical procedures. CONCLUSIONS: The commercial introduction of TMVr may be associated with growth in cardiac surgery, without detracting from other therapies, and favorable clinical outcomes for all treated mitral regurgitation patients. These findings demonstrate the potential benefits of complementary therapies in the treatment of patients with mitral regurgitation. John Wiley and Sons Inc. 2020-04-04 /pmc/articles/PMC7428655/ /pubmed/32248763 http://dx.doi.org/10.1161/JAHA.119.014874 Text en © 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Niikura, Hiroki
Gössl, Mario
Bae, Richard
Sun, Benjamin
Askew, Judah
Harris, Kevin
Mudy, Karol
Strauss, Craig
Stanberry, Larissa
Sweeney, Andrea
Sorajja, Paul
Impact of the Commercial Introduction of Transcatheter Mitral Valve Repair on Mitral Surgical Practice
title Impact of the Commercial Introduction of Transcatheter Mitral Valve Repair on Mitral Surgical Practice
title_full Impact of the Commercial Introduction of Transcatheter Mitral Valve Repair on Mitral Surgical Practice
title_fullStr Impact of the Commercial Introduction of Transcatheter Mitral Valve Repair on Mitral Surgical Practice
title_full_unstemmed Impact of the Commercial Introduction of Transcatheter Mitral Valve Repair on Mitral Surgical Practice
title_short Impact of the Commercial Introduction of Transcatheter Mitral Valve Repair on Mitral Surgical Practice
title_sort impact of the commercial introduction of transcatheter mitral valve repair on mitral surgical practice
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428655/
https://www.ncbi.nlm.nih.gov/pubmed/32248763
http://dx.doi.org/10.1161/JAHA.119.014874
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