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Tocilizumab, a Potent Interleukin-6 Receptor Inhibitor, Decreases Bone Resorption and Increases the Rate of Bacterial Infection After Tooth Extraction in Rats

PURPOSE: Our objective was to evaluate the influence of pretreatment with tocilizumab (TCZ) in bone healing after tooth extraction in rats. METHODS: Wistar male rats were equally divided into sham (ie, nonoperated), saline (both treated with 0.1 ml/kg saline), and six TCZ groups treated with 1, 2, 4...

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Detalles Bibliográficos
Autores principales:	Imaculada de Queiroz Rodrigues, Maria, Ohana de Lima Martins, Joyce, Silva, Paulo Goberlânio de Barros, Carlos Ferreira Júnior, Antônio Ernando, Quezado Lima Verde, Maria Elisa, Sousa, Fabrício Bitú, Lima Mota, Mário Rogério, Negreiros Nunes Alves, Ana Paula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association of Oral and Maxillofacial Surgeons 2020
Materias:	Dentoalveolar Surgery
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428756/ https://www.ncbi.nlm.nih.gov/pubmed/32919953 http://dx.doi.org/10.1016/j.joms.2020.08.012

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