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Modelling aerosol transport and virus exposure with numerical simulations in relation to SARS-CoV-2 transmission by inhalation indoors
We provide research findings on the physics of aerosol and droplet dispersion relevant to the hypothesized aerosol transmission of SARS-CoV-2 during the current pandemic. We utilize physics-based modeling at different levels of complexity, along with previous literature on coronaviruses, to investig...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428778/ https://www.ncbi.nlm.nih.gov/pubmed/32834511 http://dx.doi.org/10.1016/j.ssci.2020.104866 |
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author | Vuorinen, Ville Aarnio, Mia Alava, Mikko Alopaeus, Ville Atanasova, Nina Auvinen, Mikko Balasubramanian, Nallannan Bordbar, Hadi Erästö, Panu Grande, Rafael Hayward, Nick Hellsten, Antti Hostikka, Simo Hokkanen, Jyrki Kaario, Ossi Karvinen, Aku Kivistö, Ilkka Korhonen, Marko Kosonen, Risto Kuusela, Janne Lestinen, Sami Laurila, Erkki Nieminen, Heikki J. Peltonen, Petteri Pokki, Juho Puisto, Antti Råback, Peter Salmenjoki, Henri Sironen, Tarja Österberg, Monika |
author_facet | Vuorinen, Ville Aarnio, Mia Alava, Mikko Alopaeus, Ville Atanasova, Nina Auvinen, Mikko Balasubramanian, Nallannan Bordbar, Hadi Erästö, Panu Grande, Rafael Hayward, Nick Hellsten, Antti Hostikka, Simo Hokkanen, Jyrki Kaario, Ossi Karvinen, Aku Kivistö, Ilkka Korhonen, Marko Kosonen, Risto Kuusela, Janne Lestinen, Sami Laurila, Erkki Nieminen, Heikki J. Peltonen, Petteri Pokki, Juho Puisto, Antti Råback, Peter Salmenjoki, Henri Sironen, Tarja Österberg, Monika |
author_sort | Vuorinen, Ville |
collection | PubMed |
description | We provide research findings on the physics of aerosol and droplet dispersion relevant to the hypothesized aerosol transmission of SARS-CoV-2 during the current pandemic. We utilize physics-based modeling at different levels of complexity, along with previous literature on coronaviruses, to investigate the possibility of airborne transmission. The previous literature, our 0D-3D simulations by various physics-based models, and theoretical calculations, indicate that the typical size range of speech and cough originated droplets ([Formula: see text]) allows lingering in the air for [Formula: see text]) so that they could be inhaled. Consistent with the previous literature, numerical evidence on the rapid drying process of even large droplets, up to sizes [Formula: see text] , into droplet nuclei/aerosols is provided. Based on the literature and the public media sources, we provide evidence that the individuals, who have been tested positive on COVID-19, could have been exposed to aerosols/droplet nuclei by inhaling them in significant numbers e.g. [Formula: see text]. By 3D scale-resolving computational fluid dynamics (CFD) simulations, we give various examples on the transport and dilution of aerosols ([Formula: see text]) over distances [Formula: see text] in generic environments. We study susceptible and infected individuals in generic public places by Monte-Carlo modelling. The developed model takes into account the locally varying aerosol concentration levels which the susceptible accumulate via inhalation. The introduced concept, ’exposure time’ to virus containing aerosols is proposed to complement the traditional ’safety distance’ thinking. We show that the exposure time to inhale [Formula: see text] aerosols could range from [Formula: see text] to [Formula: see text] or even to [Formula: see text] depending on the situation. The Monte-Carlo simulations, along with the theory, provide clear quantitative insight to the exposure time in different public indoor environments. |
format | Online Article Text |
id | pubmed-7428778 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Authors. Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-74287782020-08-17 Modelling aerosol transport and virus exposure with numerical simulations in relation to SARS-CoV-2 transmission by inhalation indoors Vuorinen, Ville Aarnio, Mia Alava, Mikko Alopaeus, Ville Atanasova, Nina Auvinen, Mikko Balasubramanian, Nallannan Bordbar, Hadi Erästö, Panu Grande, Rafael Hayward, Nick Hellsten, Antti Hostikka, Simo Hokkanen, Jyrki Kaario, Ossi Karvinen, Aku Kivistö, Ilkka Korhonen, Marko Kosonen, Risto Kuusela, Janne Lestinen, Sami Laurila, Erkki Nieminen, Heikki J. Peltonen, Petteri Pokki, Juho Puisto, Antti Råback, Peter Salmenjoki, Henri Sironen, Tarja Österberg, Monika Saf Sci Article We provide research findings on the physics of aerosol and droplet dispersion relevant to the hypothesized aerosol transmission of SARS-CoV-2 during the current pandemic. We utilize physics-based modeling at different levels of complexity, along with previous literature on coronaviruses, to investigate the possibility of airborne transmission. The previous literature, our 0D-3D simulations by various physics-based models, and theoretical calculations, indicate that the typical size range of speech and cough originated droplets ([Formula: see text]) allows lingering in the air for [Formula: see text]) so that they could be inhaled. Consistent with the previous literature, numerical evidence on the rapid drying process of even large droplets, up to sizes [Formula: see text] , into droplet nuclei/aerosols is provided. Based on the literature and the public media sources, we provide evidence that the individuals, who have been tested positive on COVID-19, could have been exposed to aerosols/droplet nuclei by inhaling them in significant numbers e.g. [Formula: see text]. By 3D scale-resolving computational fluid dynamics (CFD) simulations, we give various examples on the transport and dilution of aerosols ([Formula: see text]) over distances [Formula: see text] in generic environments. We study susceptible and infected individuals in generic public places by Monte-Carlo modelling. The developed model takes into account the locally varying aerosol concentration levels which the susceptible accumulate via inhalation. The introduced concept, ’exposure time’ to virus containing aerosols is proposed to complement the traditional ’safety distance’ thinking. We show that the exposure time to inhale [Formula: see text] aerosols could range from [Formula: see text] to [Formula: see text] or even to [Formula: see text] depending on the situation. The Monte-Carlo simulations, along with the theory, provide clear quantitative insight to the exposure time in different public indoor environments. The Authors. Published by Elsevier Ltd. 2020-10 2020-06-11 /pmc/articles/PMC7428778/ /pubmed/32834511 http://dx.doi.org/10.1016/j.ssci.2020.104866 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Vuorinen, Ville Aarnio, Mia Alava, Mikko Alopaeus, Ville Atanasova, Nina Auvinen, Mikko Balasubramanian, Nallannan Bordbar, Hadi Erästö, Panu Grande, Rafael Hayward, Nick Hellsten, Antti Hostikka, Simo Hokkanen, Jyrki Kaario, Ossi Karvinen, Aku Kivistö, Ilkka Korhonen, Marko Kosonen, Risto Kuusela, Janne Lestinen, Sami Laurila, Erkki Nieminen, Heikki J. Peltonen, Petteri Pokki, Juho Puisto, Antti Råback, Peter Salmenjoki, Henri Sironen, Tarja Österberg, Monika Modelling aerosol transport and virus exposure with numerical simulations in relation to SARS-CoV-2 transmission by inhalation indoors |
title | Modelling aerosol transport and virus exposure with numerical simulations in relation to SARS-CoV-2 transmission by inhalation indoors |
title_full | Modelling aerosol transport and virus exposure with numerical simulations in relation to SARS-CoV-2 transmission by inhalation indoors |
title_fullStr | Modelling aerosol transport and virus exposure with numerical simulations in relation to SARS-CoV-2 transmission by inhalation indoors |
title_full_unstemmed | Modelling aerosol transport and virus exposure with numerical simulations in relation to SARS-CoV-2 transmission by inhalation indoors |
title_short | Modelling aerosol transport and virus exposure with numerical simulations in relation to SARS-CoV-2 transmission by inhalation indoors |
title_sort | modelling aerosol transport and virus exposure with numerical simulations in relation to sars-cov-2 transmission by inhalation indoors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428778/ https://www.ncbi.nlm.nih.gov/pubmed/32834511 http://dx.doi.org/10.1016/j.ssci.2020.104866 |
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