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Endothelial Sirtuin 3 Dictates Glucose Transport to Cardiomyocyte and Sensitizes Pressure Overload‐Induced Heart Failure

BACKGROUND: Alterations of energetic metabolism are suggested to be an important contributor to pressure overload (PO)‐induced heart failure. Our previous study reveals that knockout of endothelial Sirtuin 3 (SIRT3) alters glycolysis and impairs diastolic function. We hypothesize that endothelial SI...

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Detalles Bibliográficos
Autores principales: Zeng, Heng, He, Xiaochen, Chen, Jian‐Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428981/
https://www.ncbi.nlm.nih.gov/pubmed/32468895
http://dx.doi.org/10.1161/JAHA.120.015895