O‐GlcNAcylation Mediates Glucose‐Induced Alterations in Endothelial Cell Phenotype in Human Diabetes Mellitus

BACKGROUND: Posttranslational protein modification with O‐linked N‐acetylglucosamine (O‐GlcNAc) is linked to high glucose levels in type 2 diabetes mellitus (T2DM) and may alter cellular function. We sought to elucidate the involvement of O‐GlcNAc modification in endothelial dysfunction in patients...

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Detalles Bibliográficos
Autores principales: Masaki, Nobuyuki, Feng, Bihua, Bretón‐Romero, Rosa, Inagaki, Elica, Weisbrod, Robert M., Fetterman, Jessica L., Hamburg, Naomi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429031/
https://www.ncbi.nlm.nih.gov/pubmed/32508185
http://dx.doi.org/10.1161/JAHA.119.014046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429031/
https://www.ncbi.nlm.nih.gov/pubmed/32508185
http://dx.doi.org/10.1161/JAHA.119.014046

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