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Cigarette Smoking and Incident Stroke in Blacks of the Jackson Heart Study

BACKGROUND: Blacks are disproportionately affected by stroke compared with whites; however, less is known about the relationship between stroke and cigarette smoking in blacks. Therefore, we evaluated the relationship between cigarette smoking and all incident stroke in the JHS (Jackson Heart Study)...

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Autores principales: Oshunbade, Adebamike A., Yimer, Wondwosen K., Valle, Karen A., Clark, Donald, Kamimura, Daisuke, White, Wendy B., DeFilippis, Andrew P., Blaha, Michael J., Benjamin, Emelia J., O'Brien, Emily C., Mentz, Robert J., Fox, Ervin R., O'Mara, Charles S., Butler, Javed, Correa, Adolfo, Hall, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429065/
https://www.ncbi.nlm.nih.gov/pubmed/32517526
http://dx.doi.org/10.1161/JAHA.119.014990
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author Oshunbade, Adebamike A.
Yimer, Wondwosen K.
Valle, Karen A.
Clark, Donald
Kamimura, Daisuke
White, Wendy B.
DeFilippis, Andrew P.
Blaha, Michael J.
Benjamin, Emelia J.
O'Brien, Emily C.
Mentz, Robert J.
Fox, Ervin R.
O'Mara, Charles S.
Butler, Javed
Correa, Adolfo
Hall, Michael E.
author_facet Oshunbade, Adebamike A.
Yimer, Wondwosen K.
Valle, Karen A.
Clark, Donald
Kamimura, Daisuke
White, Wendy B.
DeFilippis, Andrew P.
Blaha, Michael J.
Benjamin, Emelia J.
O'Brien, Emily C.
Mentz, Robert J.
Fox, Ervin R.
O'Mara, Charles S.
Butler, Javed
Correa, Adolfo
Hall, Michael E.
author_sort Oshunbade, Adebamike A.
collection PubMed
description BACKGROUND: Blacks are disproportionately affected by stroke compared with whites; however, less is known about the relationship between stroke and cigarette smoking in blacks. Therefore, we evaluated the relationship between cigarette smoking and all incident stroke in the JHS (Jackson Heart Study). METHODS AND RESULTS: JHS participants without a history of stroke (n=4410) were classified by self‐reported baseline smoking status into current, past (smoked at least 400 cigarettes/life), or never smokers at baseline (2000–2004). Current smokers were further classified by smoking intensity (number of cigarettes smoked per day [1–19 and ≥20]) and followed up for incident stroke (through 2015). Hazard ratios (HRs) for incident stroke for current and past smoking compared with never smoking were estimated with adjusted Cox proportional hazard regression models. After adjusting for cardiovascular risk factors, the risk for stroke in current smokers was significantly higher compared with never smokers (HR, 2.48; 95% CI, 1.60–3.83) but there was no significant difference between past smokers and never smokers (HR, 1.10; 95% CI, 0.74–1.64). There was a dose‐dependent increased risk of stroke with smoking intensity (HR, 2.28 [95% CI, 1.38–3.86] and HR, 2.78 [95% CI, 1.47–5.28] for current smokers smoking 1–19 and ≥20 cigarettes/day, respectively). CONCLUSIONS: In a large cohort of blacks, current cigarette smoking was associated with a dose‐dependent higher risk of all stroke. In addition, past smokers did not have a significantly increased risk of all stroke compared with never smokers, which suggests that smoking cessation may have potential benefits in reducing the incidence of stroke in blacks.
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spelling pubmed-74290652020-08-18 Cigarette Smoking and Incident Stroke in Blacks of the Jackson Heart Study Oshunbade, Adebamike A. Yimer, Wondwosen K. Valle, Karen A. Clark, Donald Kamimura, Daisuke White, Wendy B. DeFilippis, Andrew P. Blaha, Michael J. Benjamin, Emelia J. O'Brien, Emily C. Mentz, Robert J. Fox, Ervin R. O'Mara, Charles S. Butler, Javed Correa, Adolfo Hall, Michael E. J Am Heart Assoc Original Research BACKGROUND: Blacks are disproportionately affected by stroke compared with whites; however, less is known about the relationship between stroke and cigarette smoking in blacks. Therefore, we evaluated the relationship between cigarette smoking and all incident stroke in the JHS (Jackson Heart Study). METHODS AND RESULTS: JHS participants without a history of stroke (n=4410) were classified by self‐reported baseline smoking status into current, past (smoked at least 400 cigarettes/life), or never smokers at baseline (2000–2004). Current smokers were further classified by smoking intensity (number of cigarettes smoked per day [1–19 and ≥20]) and followed up for incident stroke (through 2015). Hazard ratios (HRs) for incident stroke for current and past smoking compared with never smoking were estimated with adjusted Cox proportional hazard regression models. After adjusting for cardiovascular risk factors, the risk for stroke in current smokers was significantly higher compared with never smokers (HR, 2.48; 95% CI, 1.60–3.83) but there was no significant difference between past smokers and never smokers (HR, 1.10; 95% CI, 0.74–1.64). There was a dose‐dependent increased risk of stroke with smoking intensity (HR, 2.28 [95% CI, 1.38–3.86] and HR, 2.78 [95% CI, 1.47–5.28] for current smokers smoking 1–19 and ≥20 cigarettes/day, respectively). CONCLUSIONS: In a large cohort of blacks, current cigarette smoking was associated with a dose‐dependent higher risk of all stroke. In addition, past smokers did not have a significantly increased risk of all stroke compared with never smokers, which suggests that smoking cessation may have potential benefits in reducing the incidence of stroke in blacks. John Wiley and Sons Inc. 2020-06-10 /pmc/articles/PMC7429065/ /pubmed/32517526 http://dx.doi.org/10.1161/JAHA.119.014990 Text en © 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Oshunbade, Adebamike A.
Yimer, Wondwosen K.
Valle, Karen A.
Clark, Donald
Kamimura, Daisuke
White, Wendy B.
DeFilippis, Andrew P.
Blaha, Michael J.
Benjamin, Emelia J.
O'Brien, Emily C.
Mentz, Robert J.
Fox, Ervin R.
O'Mara, Charles S.
Butler, Javed
Correa, Adolfo
Hall, Michael E.
Cigarette Smoking and Incident Stroke in Blacks of the Jackson Heart Study
title Cigarette Smoking and Incident Stroke in Blacks of the Jackson Heart Study
title_full Cigarette Smoking and Incident Stroke in Blacks of the Jackson Heart Study
title_fullStr Cigarette Smoking and Incident Stroke in Blacks of the Jackson Heart Study
title_full_unstemmed Cigarette Smoking and Incident Stroke in Blacks of the Jackson Heart Study
title_short Cigarette Smoking and Incident Stroke in Blacks of the Jackson Heart Study
title_sort cigarette smoking and incident stroke in blacks of the jackson heart study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429065/
https://www.ncbi.nlm.nih.gov/pubmed/32517526
http://dx.doi.org/10.1161/JAHA.119.014990
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