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Comparison of ligand binding and conformational stability of human calmodulin with its homolog from the malaria parasite Plasmodium falciparum

Calmodulin (CaM), the key calcium sensor of eukaryotic cells regulating a great number of target proteins, belongs to the most conserved proteins. We compared function and properties of CaMs from two evolutionarily distant species, the human (Homo sapiens) representing vertebrates, and the malaria p...

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Detalles Bibliográficos
Autores principales: Juhász, Tünde, Kardos, József, Dürvanger, Zsolt, Harmat, Veronika, Liliom, Károly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429351/
https://www.ncbi.nlm.nih.gov/pubmed/32821880
http://dx.doi.org/10.1096/fba.2020-00013