Cargando…
Potentiating TMEM16A does not stimulate airway mucus secretion or bronchial and pulmonary arterial smooth muscle contraction
The calcium‐activated chloride channel (CaCC) TMEM16A enables chloride secretion across several transporting epithelia, including in the airways. Additional roles for TMEM16A have been proposed, which include regulating mucus production and secretion and stimulating smooth muscle contraction. The ai...
Autores principales: | Danahay, Henry, Fox, Roy, Lilley, Sarah, Charlton, Holly, Adley, Kathryn, Christie, Lee, Ansari, Ejaz, Ehre, Camille, Flen, Alexis, Tuvim, Michael J., Dickey, Burton F., Williams, Colin, Beaudoin, Sarah, Collingwood, Stephen P, Gosling, Martin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429354/ https://www.ncbi.nlm.nih.gov/pubmed/32821878 http://dx.doi.org/10.1096/fba.2020-00035 |
Ejemplares similares
-
Niclosamide does not modulate airway epithelial function through blocking of the calcium activated chloride channel, TMEM16A
por: Danahay, Henry, et al.
Publicado: (2023) -
TMEM16A Potentiation: A Novel Therapeutic Approach for the Treatment of Cystic Fibrosis
por: Danahay, Henry L., et al.
Publicado: (2020) -
TMEM16A: An Alternative Approach to Restoring Airway Anion Secretion in Cystic Fibrosis?
por: Danahay, Henry, et al.
Publicado: (2020) -
Reply to Olschewski et al.: TMEM16A Potentiation:
Possible Drawbacks
por: Danahay, Henry L., et al.
Publicado: (2020) -
Airway Mucus Dysfunction in COVID-19
por: Dickey, Burton F., et al.
Publicado: (2022)