Stochastic allelic expression as trigger for contractile imbalance in hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM), the most common inherited cardiac disease, is caused by several mostly heterozygous mutations in sarcomeric genes. Hallmarks of HCM are cardiomyocyte and myofibrillar disarray and hypertrophy and fibrosis of the septum and the left ventricle. To date, a pathomechan...

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Detalles Bibliográficos
Autores principales: Montag, Judith, Kraft, Theresia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429642/
https://www.ncbi.nlm.nih.gov/pubmed/32661905
http://dx.doi.org/10.1007/s12551-020-00719-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429642/
https://www.ncbi.nlm.nih.gov/pubmed/32661905
http://dx.doi.org/10.1007/s12551-020-00719-z

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