Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia

Neuronal circuit assembly requires the fine balance between synapse formation and elimination. Microglia, through the elimination of supernumerary synapses, have an established role in this process. While the microglial receptor TREM2 and the soluble complement proteins C1q and C3 are recognized as...

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Detalles Bibliográficos
Autores principales: Scott‐Hewitt, Nicole, Perrucci, Fabio, Morini, Raffaella, Erreni, Marco, Mahoney, Matthew, Witkowska, Agata, Carey, Alanna, Faggiani, Elisa, Schuetz, Lisa Theresia, Mason, Sydney, Tamborini, Matteo, Bizzotto, Matteo, Passoni, Lorena, Filipello, Fabia, Jahn, Reinhard, Stevens, Beth, Matteoli, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429741/
https://www.ncbi.nlm.nih.gov/pubmed/32657463
http://dx.doi.org/10.15252/embj.2020105380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429741/
https://www.ncbi.nlm.nih.gov/pubmed/32657463
http://dx.doi.org/10.15252/embj.2020105380

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