Cargando…
Repeated Induced-Membrane Technique Failure without Infection: A Series of Three Consecutive Procedures Performed for a Single Femur Defect
A 40-year-old male was treated using the induced-membrane technique (IMT) for a noninfected, 9 cm long femoral bone defect complicating a lengthening procedure. The interesting case feature lies in the three consecutive IMT procedures that were necessary to achieve complete bone repair in this unusu...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429766/ https://www.ncbi.nlm.nih.gov/pubmed/32832179 http://dx.doi.org/10.1155/2020/8892226 |
_version_ | 1783571313223270400 |
---|---|
author | Mathieu, Laurent Durand, Marjorie Demoures, Thomas Steenman, Christian Masquelet, Alain-Charles Collombet, Jean-Marc |
author_facet | Mathieu, Laurent Durand, Marjorie Demoures, Thomas Steenman, Christian Masquelet, Alain-Charles Collombet, Jean-Marc |
author_sort | Mathieu, Laurent |
collection | PubMed |
description | A 40-year-old male was treated using the induced-membrane technique (IMT) for a noninfected, 9 cm long femoral bone defect complicating a lengthening procedure. The interesting case feature lies in the three consecutive IMT procedures that were necessary to achieve complete bone repair in this unusual clinical situation. The first procedure failed because of the lack of graft revascularization likely related to an induced-membrane (IM) alteration demonstrated by histological observations. The second IMT procedure led to partial graft integration interrupted by the elongation nail breakage. At last, the third procedure fully succeeded after nail exchange and iterative iliac bone grafting. Complete bone union was achieved with a poor functional recovery one year after the last procedure and four years following the first cement spacer implantation. By means of clinical and histological observations, we demonstrated that the first and the second IMT failures had two distinct origins, namely, biological and mechanical causes, respectively. Although simple, a successful IMT procedure is not so easy to complete. |
format | Online Article Text |
id | pubmed-7429766 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-74297662020-08-20 Repeated Induced-Membrane Technique Failure without Infection: A Series of Three Consecutive Procedures Performed for a Single Femur Defect Mathieu, Laurent Durand, Marjorie Demoures, Thomas Steenman, Christian Masquelet, Alain-Charles Collombet, Jean-Marc Case Rep Orthop Case Report A 40-year-old male was treated using the induced-membrane technique (IMT) for a noninfected, 9 cm long femoral bone defect complicating a lengthening procedure. The interesting case feature lies in the three consecutive IMT procedures that were necessary to achieve complete bone repair in this unusual clinical situation. The first procedure failed because of the lack of graft revascularization likely related to an induced-membrane (IM) alteration demonstrated by histological observations. The second IMT procedure led to partial graft integration interrupted by the elongation nail breakage. At last, the third procedure fully succeeded after nail exchange and iterative iliac bone grafting. Complete bone union was achieved with a poor functional recovery one year after the last procedure and four years following the first cement spacer implantation. By means of clinical and histological observations, we demonstrated that the first and the second IMT failures had two distinct origins, namely, biological and mechanical causes, respectively. Although simple, a successful IMT procedure is not so easy to complete. Hindawi 2020-08-07 /pmc/articles/PMC7429766/ /pubmed/32832179 http://dx.doi.org/10.1155/2020/8892226 Text en Copyright © 2020 Laurent Mathieu et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Mathieu, Laurent Durand, Marjorie Demoures, Thomas Steenman, Christian Masquelet, Alain-Charles Collombet, Jean-Marc Repeated Induced-Membrane Technique Failure without Infection: A Series of Three Consecutive Procedures Performed for a Single Femur Defect |
title | Repeated Induced-Membrane Technique Failure without Infection: A Series of Three Consecutive Procedures Performed for a Single Femur Defect |
title_full | Repeated Induced-Membrane Technique Failure without Infection: A Series of Three Consecutive Procedures Performed for a Single Femur Defect |
title_fullStr | Repeated Induced-Membrane Technique Failure without Infection: A Series of Three Consecutive Procedures Performed for a Single Femur Defect |
title_full_unstemmed | Repeated Induced-Membrane Technique Failure without Infection: A Series of Three Consecutive Procedures Performed for a Single Femur Defect |
title_short | Repeated Induced-Membrane Technique Failure without Infection: A Series of Three Consecutive Procedures Performed for a Single Femur Defect |
title_sort | repeated induced-membrane technique failure without infection: a series of three consecutive procedures performed for a single femur defect |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429766/ https://www.ncbi.nlm.nih.gov/pubmed/32832179 http://dx.doi.org/10.1155/2020/8892226 |
work_keys_str_mv | AT mathieulaurent repeatedinducedmembranetechniquefailurewithoutinfectionaseriesofthreeconsecutiveproceduresperformedforasinglefemurdefect AT durandmarjorie repeatedinducedmembranetechniquefailurewithoutinfectionaseriesofthreeconsecutiveproceduresperformedforasinglefemurdefect AT demouresthomas repeatedinducedmembranetechniquefailurewithoutinfectionaseriesofthreeconsecutiveproceduresperformedforasinglefemurdefect AT steenmanchristian repeatedinducedmembranetechniquefailurewithoutinfectionaseriesofthreeconsecutiveproceduresperformedforasinglefemurdefect AT masqueletalaincharles repeatedinducedmembranetechniquefailurewithoutinfectionaseriesofthreeconsecutiveproceduresperformedforasinglefemurdefect AT collombetjeanmarc repeatedinducedmembranetechniquefailurewithoutinfectionaseriesofthreeconsecutiveproceduresperformedforasinglefemurdefect |