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Study of Factors Influencing Dry Eye in Rheumatoid Arthritis
PURPOSE: The present study investigated the relationship between dry eye and the disease activity in patients with rheumatoid arthritis (RA). METHODS: Patients with RA were divided by the Ocular Surface Disease Index (OSDI) into the symptomatic group (score ≥ 12) and the asymptomatic group (score &l...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429800/ https://www.ncbi.nlm.nih.gov/pubmed/32832136 http://dx.doi.org/10.1155/2020/5768679 |
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author | Ma, Weifang Wang, Guoliang Li, Xiaofeng Wu, Huping Liu, Zuguo Dong, Nuo Li, Cheng |
author_facet | Ma, Weifang Wang, Guoliang Li, Xiaofeng Wu, Huping Liu, Zuguo Dong, Nuo Li, Cheng |
author_sort | Ma, Weifang |
collection | PubMed |
description | PURPOSE: The present study investigated the relationship between dry eye and the disease activity in patients with rheumatoid arthritis (RA). METHODS: Patients with RA were divided by the Ocular Surface Disease Index (OSDI) into the symptomatic group (score ≥ 12) and the asymptomatic group (score < 12). By using the Disease Activity Score (DAS-28) questionnaire, they were divided into the active group (score > 2.6) and the stable group (score ≤ 2.6). In the control group, 20 healthy adults with matched sex and age were selected. RA patients and healthy adults were inspected for the tear film break time (TBUT), tear meniscus height (TMH), corneal fluorescein staining (CFS), meibomian scan (MS), meibomian gland secretion score (MSS), and eyelid margin assessment (EMS). RESULTS: The TBUT of the RA group was significantly less than that of the control group, while the CFS, MS, EMS, and MSS were higher. The TBUT of the symptomatic RA group was significantly less than that of the asymptomatic group, and the CFS was higher. In the active RA group, only the CFS was higher than that of the stable group, and there was no significant difference between the two groups for other parameters. Furthermore, there was no significant correlation between the course of RA and the dry eye (P > 0.05). CONCLUSION: The rheumatoid activity does not necessarily lead to an aggravation of dry eye. Regardless of the duration, RA was not found to exhibit relation with the severity of dry eye. Translational Relevance. RA patients with disease active period cannot be ignored for the existence of dry eye, since patients with dry eye often lack the signs and symptoms. |
format | Online Article Text |
id | pubmed-7429800 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-74298002020-08-20 Study of Factors Influencing Dry Eye in Rheumatoid Arthritis Ma, Weifang Wang, Guoliang Li, Xiaofeng Wu, Huping Liu, Zuguo Dong, Nuo Li, Cheng J Ophthalmol Research Article PURPOSE: The present study investigated the relationship between dry eye and the disease activity in patients with rheumatoid arthritis (RA). METHODS: Patients with RA were divided by the Ocular Surface Disease Index (OSDI) into the symptomatic group (score ≥ 12) and the asymptomatic group (score < 12). By using the Disease Activity Score (DAS-28) questionnaire, they were divided into the active group (score > 2.6) and the stable group (score ≤ 2.6). In the control group, 20 healthy adults with matched sex and age were selected. RA patients and healthy adults were inspected for the tear film break time (TBUT), tear meniscus height (TMH), corneal fluorescein staining (CFS), meibomian scan (MS), meibomian gland secretion score (MSS), and eyelid margin assessment (EMS). RESULTS: The TBUT of the RA group was significantly less than that of the control group, while the CFS, MS, EMS, and MSS were higher. The TBUT of the symptomatic RA group was significantly less than that of the asymptomatic group, and the CFS was higher. In the active RA group, only the CFS was higher than that of the stable group, and there was no significant difference between the two groups for other parameters. Furthermore, there was no significant correlation between the course of RA and the dry eye (P > 0.05). CONCLUSION: The rheumatoid activity does not necessarily lead to an aggravation of dry eye. Regardless of the duration, RA was not found to exhibit relation with the severity of dry eye. Translational Relevance. RA patients with disease active period cannot be ignored for the existence of dry eye, since patients with dry eye often lack the signs and symptoms. Hindawi 2020-08-08 /pmc/articles/PMC7429800/ /pubmed/32832136 http://dx.doi.org/10.1155/2020/5768679 Text en Copyright © 2020 Weifang Ma et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Ma, Weifang Wang, Guoliang Li, Xiaofeng Wu, Huping Liu, Zuguo Dong, Nuo Li, Cheng Study of Factors Influencing Dry Eye in Rheumatoid Arthritis |
title | Study of Factors Influencing Dry Eye in Rheumatoid Arthritis |
title_full | Study of Factors Influencing Dry Eye in Rheumatoid Arthritis |
title_fullStr | Study of Factors Influencing Dry Eye in Rheumatoid Arthritis |
title_full_unstemmed | Study of Factors Influencing Dry Eye in Rheumatoid Arthritis |
title_short | Study of Factors Influencing Dry Eye in Rheumatoid Arthritis |
title_sort | study of factors influencing dry eye in rheumatoid arthritis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429800/ https://www.ncbi.nlm.nih.gov/pubmed/32832136 http://dx.doi.org/10.1155/2020/5768679 |
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