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Triggering a switch from basal- to luminal-like breast cancer subtype by the small-molecule diptoindonesin G via induction of GABARAPL1

Breast cancer is a heterogeneous disease that includes different molecular subtypes. The basal-like subtype has a poor prognosis and a high recurrence rate, whereas the luminal-like subtype confers a more favorable patient prognosis partially due to anti-hormone therapy responsiveness. Here, we demo...

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Detalles Bibliográficos
Autores principales: Fan, Minmin, Chen, Jingwei, Gao, Jian, Xue, Wenwen, Wang, Yixuan, Li, Wuhao, Zhou, Lin, Li, Xin, Jiang, Chengfei, Sun, Yang, Wu, Xuefeng, Wu, Xudong, Ge, Huiming, Shen, Yan, Xu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429843/
https://www.ncbi.nlm.nih.gov/pubmed/32801338
http://dx.doi.org/10.1038/s41419-020-02878-z