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Antifungal drug miconazole ameliorated memory deficits in a mouse model of LPS-induced memory loss through targeting iNOS
Alzheimer’s disease (AD) is closely related to neuroinflammation, and the increase in inflammatory cytokine generation and inducible nitric oxide synthase (iNOS) expression in the brain of a patient with AD is well known. Excessive cytokines can stimulate iNOS in microglia and astroglia and overprod...
Autores principales: | Yeo, In Jun, Yun, Jaesuk, Son, Dong Ju, Han, Sang-Bae, Hong, Jin Tae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429861/ https://www.ncbi.nlm.nih.gov/pubmed/32796824 http://dx.doi.org/10.1038/s41419-020-2619-5 |
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