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miR-16 integrates signal pathways in myofibroblasts: determinant of cell fate necessary for fibrosis resolution
Liver fibrosis is characterized by the transdifferentiation of hepatic stellate cells (HSCs) to myofibroblasts and poor response to treatment. This can be attributed to the myofibroblast-specific resistance to phenotype reversal. In this study, we complemented miR-16 into miR-16-deficient myofibrobl...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429878/ https://www.ncbi.nlm.nih.gov/pubmed/32801294 http://dx.doi.org/10.1038/s41419-020-02832-z |