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Drp1 modulates mitochondrial stress responses to mitotic arrest

Antimitotic drugs are extensively used in the clinics to treat different types of cancer. They can retain cells in a prolonged mitotic arrest imposing two major fates, mitotic slippage, or mitotic cell death. While the former is molecularly well characterized, the mechanisms that control mitotic cel...

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Detalles Bibliográficos
Autores principales: Peña-Blanco, Aida, Haschka, Manuel D., Jenner, Andreas, Zuleger, Theresia, Proikas-Cezanne, Tassula, Villunger, Andreas, García-Sáez, Ana J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429963/
https://www.ncbi.nlm.nih.gov/pubmed/32203171
http://dx.doi.org/10.1038/s41418-020-0527-y