A novel culture method that sustains ERα signaling in human breast cancer tissue microstructures

BACKGROUND: Estrogen receptor α (ERα) signaling is a defining and driving event in most breast cancers; ERα is detected in malignant epithelial cells of 75% of all breast cancers (classified as ER-positive breast cancer) and, in these cases, ERα targeting is the main therapeutic strategy. However, t...

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Detalles Bibliográficos
Autores principales: Cartaxo, Ana Luísa, Estrada, Marta F., Domenici, Giacomo, Roque, Ruben, Silva, Fernanda, Gualda, Emilio J., Loza-Alvarez, Pablo, Sflomos, George, Brisken, Cathrin, Alves, Paula M., André, Saudade, Brito, Catarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430012/
https://www.ncbi.nlm.nih.gov/pubmed/32807212
http://dx.doi.org/10.1186/s13046-020-01653-4

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