Cargando…

Endoscopic Submucosal Tunnel Dissection as a Novel Therapeutic Technique in Patients With Barrett’s Esophagus

With the ameliorated resectability prowess of endoscopic techniques, a myriad of diseases previously treated by major ablative surgeries are now endoscopically curable. Endoscopic submucosal tunnel dissection (ESTD) is a relatively new technique that has diversified endoscopic application. Although...

Descripción completa

Detalles Bibliográficos
Autores principales: Inayat, Faisal, Weissman, Simcha, Malik, Adnan, Munir, Badria, Iqbal, Shahzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430079/
https://www.ncbi.nlm.nih.gov/pubmed/32666847
http://dx.doi.org/10.1177/2324709620941318
_version_ 1783571367903363072
author Inayat, Faisal
Weissman, Simcha
Malik, Adnan
Munir, Badria
Iqbal, Shahzad
author_facet Inayat, Faisal
Weissman, Simcha
Malik, Adnan
Munir, Badria
Iqbal, Shahzad
author_sort Inayat, Faisal
collection PubMed
description With the ameliorated resectability prowess of endoscopic techniques, a myriad of diseases previously treated by major ablative surgeries are now endoscopically curable. Endoscopic submucosal tunnel dissection (ESTD) is a relatively new technique that has diversified endoscopic application. Although ESTD has frequently been used for the resection of esophageal neoplastic lesions, the clinical evidence pertaining to its efficacy in the treatment of circumferential Barrett’s esophagus remains sparse. In this study, we evaluated ESTD as a potential therapeutic technique in patients with Barrett’s esophagus-related high-grade dysplasia. The tunneling strategy helped achieve complete en bloc resection at an increased dissection speed, without any procedural complications. This article illustrates that ESTD can be a feasible, safe, and effective treatment for dysplastic Barrett’s esophagus. Future research should aim to stratify the potential risks and complications associated with this optimization of endoscopic submucosal dissection in patients with superficial esophageal lesions.
format Online
Article
Text
id pubmed-7430079
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-74300792020-08-27 Endoscopic Submucosal Tunnel Dissection as a Novel Therapeutic Technique in Patients With Barrett’s Esophagus Inayat, Faisal Weissman, Simcha Malik, Adnan Munir, Badria Iqbal, Shahzad J Investig Med High Impact Case Rep Case Report With the ameliorated resectability prowess of endoscopic techniques, a myriad of diseases previously treated by major ablative surgeries are now endoscopically curable. Endoscopic submucosal tunnel dissection (ESTD) is a relatively new technique that has diversified endoscopic application. Although ESTD has frequently been used for the resection of esophageal neoplastic lesions, the clinical evidence pertaining to its efficacy in the treatment of circumferential Barrett’s esophagus remains sparse. In this study, we evaluated ESTD as a potential therapeutic technique in patients with Barrett’s esophagus-related high-grade dysplasia. The tunneling strategy helped achieve complete en bloc resection at an increased dissection speed, without any procedural complications. This article illustrates that ESTD can be a feasible, safe, and effective treatment for dysplastic Barrett’s esophagus. Future research should aim to stratify the potential risks and complications associated with this optimization of endoscopic submucosal dissection in patients with superficial esophageal lesions. SAGE Publications 2020-07-15 /pmc/articles/PMC7430079/ /pubmed/32666847 http://dx.doi.org/10.1177/2324709620941318 Text en © 2020 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Inayat, Faisal
Weissman, Simcha
Malik, Adnan
Munir, Badria
Iqbal, Shahzad
Endoscopic Submucosal Tunnel Dissection as a Novel Therapeutic Technique in Patients With Barrett’s Esophagus
title Endoscopic Submucosal Tunnel Dissection as a Novel Therapeutic Technique in Patients With Barrett’s Esophagus
title_full Endoscopic Submucosal Tunnel Dissection as a Novel Therapeutic Technique in Patients With Barrett’s Esophagus
title_fullStr Endoscopic Submucosal Tunnel Dissection as a Novel Therapeutic Technique in Patients With Barrett’s Esophagus
title_full_unstemmed Endoscopic Submucosal Tunnel Dissection as a Novel Therapeutic Technique in Patients With Barrett’s Esophagus
title_short Endoscopic Submucosal Tunnel Dissection as a Novel Therapeutic Technique in Patients With Barrett’s Esophagus
title_sort endoscopic submucosal tunnel dissection as a novel therapeutic technique in patients with barrett’s esophagus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430079/
https://www.ncbi.nlm.nih.gov/pubmed/32666847
http://dx.doi.org/10.1177/2324709620941318
work_keys_str_mv AT inayatfaisal endoscopicsubmucosaltunneldissectionasanoveltherapeutictechniqueinpatientswithbarrettsesophagus
AT weissmansimcha endoscopicsubmucosaltunneldissectionasanoveltherapeutictechniqueinpatientswithbarrettsesophagus
AT malikadnan endoscopicsubmucosaltunneldissectionasanoveltherapeutictechniqueinpatientswithbarrettsesophagus
AT munirbadria endoscopicsubmucosaltunneldissectionasanoveltherapeutictechniqueinpatientswithbarrettsesophagus
AT iqbalshahzad endoscopicsubmucosaltunneldissectionasanoveltherapeutictechniqueinpatientswithbarrettsesophagus