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Efficacy of a new dietary supplement in dogs with advanced chronic kidney disease

Chronic kidney disease (CKD) is a common disease in elderly dogs. The present study aims to evaluate the efficacy of a dietary supplement containing calcium carbonate, calcium-lactate gluconate, chitosan and sodium bicarbonate in dogs with IRIS stage 3 of CKD. Twenty dogs were enrolled in the study,...

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Autores principales: Martello, Elisa, Perondi, Francesca, Capucchio, Maria Teresa, Biasato, Ilaria, Biasibetti, Elena, Cocca, Tiziana, Bruni, Natascia, Lippi, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430264/
https://www.ncbi.nlm.nih.gov/pubmed/32864210
http://dx.doi.org/10.7717/peerj.9663
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author Martello, Elisa
Perondi, Francesca
Capucchio, Maria Teresa
Biasato, Ilaria
Biasibetti, Elena
Cocca, Tiziana
Bruni, Natascia
Lippi, Ilaria
author_facet Martello, Elisa
Perondi, Francesca
Capucchio, Maria Teresa
Biasato, Ilaria
Biasibetti, Elena
Cocca, Tiziana
Bruni, Natascia
Lippi, Ilaria
author_sort Martello, Elisa
collection PubMed
description Chronic kidney disease (CKD) is a common disease in elderly dogs. The present study aims to evaluate the efficacy of a dietary supplement containing calcium carbonate, calcium-lactate gluconate, chitosan and sodium bicarbonate in dogs with IRIS stage 3 of CKD. Twenty dogs were enrolled in the study, ten were administered the new dietary supplementation for 180 days (T group) while the others were used as control group (C group). Haematologic, biochemical and urinalysis were performed every 30 days. A significant reduction in the T group compared to the C group in serum phosphorus level and increase in serum bicarbonate and ionized calcium values were recorded. The urine protein-to-creatinine ratio (UPC) was significantly lower in the T group at the end of the study compared to the C group. The tested supplement could be considered as a supportive treatment for dogs with advanced CKD.
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spelling pubmed-74302642020-08-27 Efficacy of a new dietary supplement in dogs with advanced chronic kidney disease Martello, Elisa Perondi, Francesca Capucchio, Maria Teresa Biasato, Ilaria Biasibetti, Elena Cocca, Tiziana Bruni, Natascia Lippi, Ilaria PeerJ Food Science and Technology Chronic kidney disease (CKD) is a common disease in elderly dogs. The present study aims to evaluate the efficacy of a dietary supplement containing calcium carbonate, calcium-lactate gluconate, chitosan and sodium bicarbonate in dogs with IRIS stage 3 of CKD. Twenty dogs were enrolled in the study, ten were administered the new dietary supplementation for 180 days (T group) while the others were used as control group (C group). Haematologic, biochemical and urinalysis were performed every 30 days. A significant reduction in the T group compared to the C group in serum phosphorus level and increase in serum bicarbonate and ionized calcium values were recorded. The urine protein-to-creatinine ratio (UPC) was significantly lower in the T group at the end of the study compared to the C group. The tested supplement could be considered as a supportive treatment for dogs with advanced CKD. PeerJ Inc. 2020-08-14 /pmc/articles/PMC7430264/ /pubmed/32864210 http://dx.doi.org/10.7717/peerj.9663 Text en ©2020 Martello et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Food Science and Technology
Martello, Elisa
Perondi, Francesca
Capucchio, Maria Teresa
Biasato, Ilaria
Biasibetti, Elena
Cocca, Tiziana
Bruni, Natascia
Lippi, Ilaria
Efficacy of a new dietary supplement in dogs with advanced chronic kidney disease
title Efficacy of a new dietary supplement in dogs with advanced chronic kidney disease
title_full Efficacy of a new dietary supplement in dogs with advanced chronic kidney disease
title_fullStr Efficacy of a new dietary supplement in dogs with advanced chronic kidney disease
title_full_unstemmed Efficacy of a new dietary supplement in dogs with advanced chronic kidney disease
title_short Efficacy of a new dietary supplement in dogs with advanced chronic kidney disease
title_sort efficacy of a new dietary supplement in dogs with advanced chronic kidney disease
topic Food Science and Technology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430264/
https://www.ncbi.nlm.nih.gov/pubmed/32864210
http://dx.doi.org/10.7717/peerj.9663
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