Photodynamic and sonodynamic therapy of acute hypoxemic respiratory failure in patients with COVID-19

• COVID-19 is largely localized in lungs. • SARS-CoV-2 binds to the heme groups in hemoglobin that leads to severe hypoxia. • Porphyrin-based photosensitizers (PS) act as a ‘decoy’ in which the SARS-CoV-2 virions would attach to PS molecules. • Photoactivation capable of destroying the bonded SARS-C...

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Autores principales: Kipshidze, Nicholas, Yeo, Nicholas, Kipshidze, Nodar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430283/
https://www.ncbi.nlm.nih.gov/pubmed/32818638
http://dx.doi.org/10.1016/j.pdpdt.2020.101961
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author Kipshidze, Nicholas
Yeo, Nicholas
Kipshidze, Nodar
author_facet Kipshidze, Nicholas
Yeo, Nicholas
Kipshidze, Nodar
author_sort Kipshidze, Nicholas
collection PubMed
description • COVID-19 is largely localized in lungs. • SARS-CoV-2 binds to the heme groups in hemoglobin that leads to severe hypoxia. • Porphyrin-based photosensitizers (PS) act as a ‘decoy’ in which the SARS-CoV-2 virions would attach to PS molecules. • Photoactivation capable of destroying the bonded SARS-CoV-2 virions.
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spelling pubmed-74302832020-08-18 Photodynamic and sonodynamic therapy of acute hypoxemic respiratory failure in patients with COVID-19 Kipshidze, Nicholas Yeo, Nicholas Kipshidze, Nodar Photodiagnosis Photodyn Ther Letter to the Editor • COVID-19 is largely localized in lungs. • SARS-CoV-2 binds to the heme groups in hemoglobin that leads to severe hypoxia. • Porphyrin-based photosensitizers (PS) act as a ‘decoy’ in which the SARS-CoV-2 virions would attach to PS molecules. • Photoactivation capable of destroying the bonded SARS-CoV-2 virions. Elsevier B.V. 2020-09 2020-08-17 /pmc/articles/PMC7430283/ /pubmed/32818638 http://dx.doi.org/10.1016/j.pdpdt.2020.101961 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Letter to the Editor
Kipshidze, Nicholas
Yeo, Nicholas
Kipshidze, Nodar
Photodynamic and sonodynamic therapy of acute hypoxemic respiratory failure in patients with COVID-19
title Photodynamic and sonodynamic therapy of acute hypoxemic respiratory failure in patients with COVID-19
title_full Photodynamic and sonodynamic therapy of acute hypoxemic respiratory failure in patients with COVID-19
title_fullStr Photodynamic and sonodynamic therapy of acute hypoxemic respiratory failure in patients with COVID-19
title_full_unstemmed Photodynamic and sonodynamic therapy of acute hypoxemic respiratory failure in patients with COVID-19
title_short Photodynamic and sonodynamic therapy of acute hypoxemic respiratory failure in patients with COVID-19
title_sort photodynamic and sonodynamic therapy of acute hypoxemic respiratory failure in patients with covid-19
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430283/
https://www.ncbi.nlm.nih.gov/pubmed/32818638
http://dx.doi.org/10.1016/j.pdpdt.2020.101961
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