Systemic AAV10.COMP-Ang1 rescues renal glomeruli and pancreatic islets in type 2 diabetic mice

INTRODUCTION: Diabetic hyperglycemia causes progressive and generalized damage to the microvasculature. In renal glomeruli, this results in the loss of podocytes with consequent loss of constitutive angiopoietin-1 (Ang1) signaling, which is required for stability of the glomerular endothelium. Repea...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Mi, Carroll, Lara S, Tang, Li, Uehara, Hironori, Westenfelder, Christof, Ambati, Balamurali K, Huang, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Pathophysiology/Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430492/
https://www.ncbi.nlm.nih.gov/pubmed/32792355
http://dx.doi.org/10.1136/bmjdrc-2019-000882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430492/
https://www.ncbi.nlm.nih.gov/pubmed/32792355
http://dx.doi.org/10.1136/bmjdrc-2019-000882

Ejemplares similares