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Reconciling Functional MRI Findings With Intraoperative Anatomy in Brain Tumor Surgery: Stereotactic-Guided Resection of Glioma in Broca’s Area

Stereotactic navigation and functional magnetic resonance imaging (fMRI) are increasingly used as important tools for intraoperative guidance and preoperative mapping for lesions in eloquent areas. We report a case in which a WHO grade II oligodendroglioma in Broca’s area with functional activation...

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Detalles Bibliográficos
Autores principales: Fabian, Constantin, Watson, Joe C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430548/
https://www.ncbi.nlm.nih.gov/pubmed/32821571
http://dx.doi.org/10.7759/cureus.9220
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author Fabian, Constantin
Watson, Joe C
author_facet Fabian, Constantin
Watson, Joe C
author_sort Fabian, Constantin
collection PubMed
description Stereotactic navigation and functional magnetic resonance imaging (fMRI) are increasingly used as important tools for intraoperative guidance and preoperative mapping for lesions in eloquent areas. We report a case in which a WHO grade II oligodendroglioma in Broca’s area with functional activation was successfully resected with the support of blood-oxygen-level-dependent imaging (BOLD)-fMRI mapping in a patient who refused an awake craniotomy. This case highlights key principles of tumor surgery navigation. Specifically, it calls into question the utility of awake craniotomy in this modern era. Ultimately, fMRI is an important tool for tumor resections and can limit the need for more expensive or invasive measures. 
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spelling pubmed-74305482020-08-18 Reconciling Functional MRI Findings With Intraoperative Anatomy in Brain Tumor Surgery: Stereotactic-Guided Resection of Glioma in Broca’s Area Fabian, Constantin Watson, Joe C Cureus Neurology Stereotactic navigation and functional magnetic resonance imaging (fMRI) are increasingly used as important tools for intraoperative guidance and preoperative mapping for lesions in eloquent areas. We report a case in which a WHO grade II oligodendroglioma in Broca’s area with functional activation was successfully resected with the support of blood-oxygen-level-dependent imaging (BOLD)-fMRI mapping in a patient who refused an awake craniotomy. This case highlights key principles of tumor surgery navigation. Specifically, it calls into question the utility of awake craniotomy in this modern era. Ultimately, fMRI is an important tool for tumor resections and can limit the need for more expensive or invasive measures.  Cureus 2020-07-16 /pmc/articles/PMC7430548/ /pubmed/32821571 http://dx.doi.org/10.7759/cureus.9220 Text en Copyright © 2020, Fabian et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Fabian, Constantin
Watson, Joe C
Reconciling Functional MRI Findings With Intraoperative Anatomy in Brain Tumor Surgery: Stereotactic-Guided Resection of Glioma in Broca’s Area
title Reconciling Functional MRI Findings With Intraoperative Anatomy in Brain Tumor Surgery: Stereotactic-Guided Resection of Glioma in Broca’s Area
title_full Reconciling Functional MRI Findings With Intraoperative Anatomy in Brain Tumor Surgery: Stereotactic-Guided Resection of Glioma in Broca’s Area
title_fullStr Reconciling Functional MRI Findings With Intraoperative Anatomy in Brain Tumor Surgery: Stereotactic-Guided Resection of Glioma in Broca’s Area
title_full_unstemmed Reconciling Functional MRI Findings With Intraoperative Anatomy in Brain Tumor Surgery: Stereotactic-Guided Resection of Glioma in Broca’s Area
title_short Reconciling Functional MRI Findings With Intraoperative Anatomy in Brain Tumor Surgery: Stereotactic-Guided Resection of Glioma in Broca’s Area
title_sort reconciling functional mri findings with intraoperative anatomy in brain tumor surgery: stereotactic-guided resection of glioma in broca’s area
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430548/
https://www.ncbi.nlm.nih.gov/pubmed/32821571
http://dx.doi.org/10.7759/cureus.9220
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