A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model

The emergence of SARS-CoV-2 led to pandemic spread of coronavirus disease 2019 (COVID-19), manifesting with respiratory symptoms and multi-organ dysfunction. Detailed characterization of virus-neutralizing antibodies and target epitopes is needed to understand COVID-19 pathophysiology and guide immu...

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Autores principales: Kreye, Jakob, Reincke, S Momsen, Kornau, Hans-Christian, Sánchez-Sendin, Elisa, Max Corman, Victor, Liu, Hejun, Yuan, Meng, Wu, Nicholas C., Zhu, Xueyong, Lee, Chang-Chun D., Trimpert, Jakob, Höltje, Markus, Dietert, Kristina, Stöffler, Laura, von Wardenburg, Niels, van Hoof, Scott, Homeyer, Marie A, Hoffmann, Julius, Abdelgawad, Azza, Gruber, Achim D, Bertzbach, Luca D, Vladimirova, Daria, Li, Lucie Y, Barthel, Paula Charlotte, Skriner, Karl, Hocke, Andreas C, Hippenstiel, Stefan, Witzenrath, Martin, Suttorp, Norbert, Kurth, Florian, Franke, Christiana, Endres, Matthias, Schmitz, Dietmar, Jeworowski, Lara Maria, Richter, Anja, Schmidt, Marie Luisa, Schwarz, Tatjana, Müller, Marcel Alexander, Drosten, Christian, Wendisch, Daniel, Sander, Leif E, Osterrieder, Nikolaus, Wilson, Ian A, Prüss, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430590/
https://www.ncbi.nlm.nih.gov/pubmed/32817952
http://dx.doi.org/10.1101/2020.08.15.252320

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