MicroRNA dilution during oocyte growth disables the microRNA pathway in mammalian oocytes

MicroRNAs (miRNAs) are ubiquitous small RNAs guiding post-transcriptional gene repression in countless biological processes. However, the miRNA pathway in mouse oocytes appears inactive and dispensable for development. We propose that marginalization of the miRNA pathway activity stems from the cons...

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Detalles Bibliográficos
Autores principales: Kataruka, Shubhangini, Modrak, Martin, Kinterova, Veronika, Malik, Radek, Zeitler, Daniela M, Horvat, Filip, Kanka, Jiri, Meister, Gunter, Svoboda, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430632/
https://www.ncbi.nlm.nih.gov/pubmed/32609824
http://dx.doi.org/10.1093/nar/gkaa543

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