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A critical analysis of methods used to investigate the cellular uptake and subcellular localization of RNA therapeutics
RNA therapeutics are a promising strategy to treat genetic diseases caused by the overexpression or aberrant splicing of a specific protein. The field has seen major strides in the clinical efficacy of this class of molecules, largely due to chemical modifications and delivery strategies that improv...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430645/ https://www.ncbi.nlm.nih.gov/pubmed/32644123 http://dx.doi.org/10.1093/nar/gkaa576 |