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Binding of a viral IRES to the 40S subunit occurs in two successive steps mediated by eS25

The mechanism for how internal ribosome entry sites (IRESs) recruit ribosomes to initiate translation of an mRNA is not completely understood. We investigated how a 40S subunit was recruited by the cricket paralysis virus intergenic region (CrPV IGR) IRES to form a stable 40S–IRES complex. Kinetic b...

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Detalles Bibliográficos
Autores principales:	Walters, Beth, Axhemi, Armend, Jankowsky, Eckhard, Thompson, Sunnie R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430650/ https://www.ncbi.nlm.nih.gov/pubmed/32609821 http://dx.doi.org/10.1093/nar/gkaa547

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