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Necdin regulates BMAL1 stability and circadian clock through SGT1-HSP90 chaperone machinery
Circadian clocks are endogenous oscillators that control ∼24-hour physiology and behaviors in virtually all organisms. The circadian oscillator comprises interconnected transcriptional and translational feedback loops, but also requires finely coordinated protein homeostasis including protein degrad...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430654/ https://www.ncbi.nlm.nih.gov/pubmed/32667666 http://dx.doi.org/10.1093/nar/gkaa601 |