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Specificity in the biosynthesis of the universal tRNA nucleoside N(6)-threonylcarbamoyl adenosine (t(6)A)—TsaD is the gatekeeper

N(6)-threonylcarbamoyl adenosine (t(6)A) is a nucleoside modification found in all kingdoms of life at position 37 of tRNAs decoding ANN codons, which functions in part to restrict translation initiation to AUG and suppress frameshifting at tandem ANN codons. In Bacteria the proteins TsaB, TsaC (or...

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Detalles Bibliográficos
Autores principales:	Swinehart, William, Deutsch, Christopher, Sarachan, Kathryn L., Luthra, Amit, Bacusmo, Jo Marie, de Crécy-Lagard, Valérie, Swairjo, Manal A., Agris, Paul F., Iwata-Reuyl, Dirk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430679/ https://www.ncbi.nlm.nih.gov/pubmed/32385138 http://dx.doi.org/10.1261/rna.075747.120

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