Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages

Only a single drug against schistosomiasis is currently available and new drug development is urgently required but very few drug targets have been validated and characterised. However, regulatory systems including cyclic nucleotide metabolism are emerging as primary candidates for drug discovery. H...

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Detalles Bibliográficos
Autores principales: Munday, Jane C., Kunz, Stefan, Kalejaiye, Titilola D., Siderius, Marco, Schroeder, Susanne, Paape, Daniel, Alghamdi, Ali H., Abbasi, Zainab, Huang, Sheng Xiang, Donachie, Anne-Marie, William, Samia, Sabra, Abdel Nasser, Sterk, Geert Jan, Botros, Sanaa S., Brown, David G., Hoffman, Charles S., Leurs, Rob, de Koning, Harry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430754/
https://www.ncbi.nlm.nih.gov/pubmed/32730343
http://dx.doi.org/10.1371/journal.pntd.0008447

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