Severe Peripheral Neuropathy From Treatment With Arsenic Trioxide in a Patient Suffering From Acute Promyelocytic Leukemia

Treatment with arsenic trioxide (ATO) and all-trans retinoic acid (ATRA) is standard treatment for patients suffering from acute promyelocytic leukemia (APL). Peripheral neuropathy is a common sign of arsenic poisoning but reports of peripheral neuropathy from patients treated with ATO for APL are l...

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Autores principales: Helso, Soren Niemi, Roug, Anne Stidsholt, Mork, Morten, Maksten, Eva Futtrup, Severinsen, Marianne Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430865/
https://www.ncbi.nlm.nih.gov/pubmed/32855758
http://dx.doi.org/10.14740/jh617
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author Helso, Soren Niemi
Roug, Anne Stidsholt
Mork, Morten
Maksten, Eva Futtrup
Severinsen, Marianne Tang
author_facet Helso, Soren Niemi
Roug, Anne Stidsholt
Mork, Morten
Maksten, Eva Futtrup
Severinsen, Marianne Tang
author_sort Helso, Soren Niemi
collection PubMed
description Treatment with arsenic trioxide (ATO) and all-trans retinoic acid (ATRA) is standard treatment for patients suffering from acute promyelocytic leukemia (APL). Peripheral neuropathy is a common sign of arsenic poisoning but reports of peripheral neuropathy from patients treated with ATO for APL are limited. We here present a case of a woman treated with standard regimes of ATRA-ATO for APL, who subsequently developed severe peripheral neuropathy from ATO poisoning.
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spelling pubmed-74308652020-09-01 Severe Peripheral Neuropathy From Treatment With Arsenic Trioxide in a Patient Suffering From Acute Promyelocytic Leukemia Helso, Soren Niemi Roug, Anne Stidsholt Mork, Morten Maksten, Eva Futtrup Severinsen, Marianne Tang J Hematol Case Report Treatment with arsenic trioxide (ATO) and all-trans retinoic acid (ATRA) is standard treatment for patients suffering from acute promyelocytic leukemia (APL). Peripheral neuropathy is a common sign of arsenic poisoning but reports of peripheral neuropathy from patients treated with ATO for APL are limited. We here present a case of a woman treated with standard regimes of ATRA-ATO for APL, who subsequently developed severe peripheral neuropathy from ATO poisoning. Elmer Press 2020-09 2020-08-14 /pmc/articles/PMC7430865/ /pubmed/32855758 http://dx.doi.org/10.14740/jh617 Text en Copyright 2020, Helso et al. http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Helso, Soren Niemi
Roug, Anne Stidsholt
Mork, Morten
Maksten, Eva Futtrup
Severinsen, Marianne Tang
Severe Peripheral Neuropathy From Treatment With Arsenic Trioxide in a Patient Suffering From Acute Promyelocytic Leukemia
title Severe Peripheral Neuropathy From Treatment With Arsenic Trioxide in a Patient Suffering From Acute Promyelocytic Leukemia
title_full Severe Peripheral Neuropathy From Treatment With Arsenic Trioxide in a Patient Suffering From Acute Promyelocytic Leukemia
title_fullStr Severe Peripheral Neuropathy From Treatment With Arsenic Trioxide in a Patient Suffering From Acute Promyelocytic Leukemia
title_full_unstemmed Severe Peripheral Neuropathy From Treatment With Arsenic Trioxide in a Patient Suffering From Acute Promyelocytic Leukemia
title_short Severe Peripheral Neuropathy From Treatment With Arsenic Trioxide in a Patient Suffering From Acute Promyelocytic Leukemia
title_sort severe peripheral neuropathy from treatment with arsenic trioxide in a patient suffering from acute promyelocytic leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430865/
https://www.ncbi.nlm.nih.gov/pubmed/32855758
http://dx.doi.org/10.14740/jh617
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