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A Study of Artificial Sweeteners and Thyroid Cancer Risk
BACKGROUND: In recent decades, data from certain observational studies have stirred controversy over artificial sweeteners by linking them with certain malignancies. As the incidences of artificial sweetener consumption and thyroid cancer are both increasing, our study aimed to determine any possibl...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elmer Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430875/ https://www.ncbi.nlm.nih.gov/pubmed/32849937 http://dx.doi.org/10.14740/jocmr4258 |
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author | Singh, Navdeep Singh Lubana, Sandeep Arora, Saurabh Sachmechi, Issac |
author_facet | Singh, Navdeep Singh Lubana, Sandeep Arora, Saurabh Sachmechi, Issac |
author_sort | Singh, Navdeep |
collection | PubMed |
description | BACKGROUND: In recent decades, data from certain observational studies have stirred controversy over artificial sweeteners by linking them with certain malignancies. As the incidences of artificial sweetener consumption and thyroid cancer are both increasing, our study aimed to determine any possible association between them. METHODS: This retrospective observational study enrolled 50 patients (group 1) with proven diagnosis of well-differentiated thyroid cancer (WDTC) and 50 control subjects (group 2) diagnosed as having benign thyroid nodule by fine-needle aspiration. The survey questionnaire included the total amount and duration of intake of artificial sweeteners. RESULTS: Increased consumption of artificial sweeteners was noted in group 1 as compared to group 2, which was statistically significant (76% vs. 24%, P < 0.01). This study suggested that the use of an average of four packets (4 g) per day of artificial sweetener for an average duration of 5 years is associated with WDTC. CONCLUSIONS: Our study emphasizes the significance of artificial sweetener consumption as a potential risk factor for WDTC and increase in public awareness regarding this association if other studies in future report similar findings. |
format | Online Article Text |
id | pubmed-7430875 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elmer Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-74308752020-08-25 A Study of Artificial Sweeteners and Thyroid Cancer Risk Singh, Navdeep Singh Lubana, Sandeep Arora, Saurabh Sachmechi, Issac J Clin Med Res Original Article BACKGROUND: In recent decades, data from certain observational studies have stirred controversy over artificial sweeteners by linking them with certain malignancies. As the incidences of artificial sweetener consumption and thyroid cancer are both increasing, our study aimed to determine any possible association between them. METHODS: This retrospective observational study enrolled 50 patients (group 1) with proven diagnosis of well-differentiated thyroid cancer (WDTC) and 50 control subjects (group 2) diagnosed as having benign thyroid nodule by fine-needle aspiration. The survey questionnaire included the total amount and duration of intake of artificial sweeteners. RESULTS: Increased consumption of artificial sweeteners was noted in group 1 as compared to group 2, which was statistically significant (76% vs. 24%, P < 0.01). This study suggested that the use of an average of four packets (4 g) per day of artificial sweetener for an average duration of 5 years is associated with WDTC. CONCLUSIONS: Our study emphasizes the significance of artificial sweetener consumption as a potential risk factor for WDTC and increase in public awareness regarding this association if other studies in future report similar findings. Elmer Press 2020-08 2020-07-01 /pmc/articles/PMC7430875/ /pubmed/32849937 http://dx.doi.org/10.14740/jocmr4258 Text en Copyright 2020, Singh et al. http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Singh, Navdeep Singh Lubana, Sandeep Arora, Saurabh Sachmechi, Issac A Study of Artificial Sweeteners and Thyroid Cancer Risk |
title | A Study of Artificial Sweeteners and Thyroid Cancer Risk |
title_full | A Study of Artificial Sweeteners and Thyroid Cancer Risk |
title_fullStr | A Study of Artificial Sweeteners and Thyroid Cancer Risk |
title_full_unstemmed | A Study of Artificial Sweeteners and Thyroid Cancer Risk |
title_short | A Study of Artificial Sweeteners and Thyroid Cancer Risk |
title_sort | study of artificial sweeteners and thyroid cancer risk |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430875/ https://www.ncbi.nlm.nih.gov/pubmed/32849937 http://dx.doi.org/10.14740/jocmr4258 |
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