Cargando…

A Study of Artificial Sweeteners and Thyroid Cancer Risk

BACKGROUND: In recent decades, data from certain observational studies have stirred controversy over artificial sweeteners by linking them with certain malignancies. As the incidences of artificial sweetener consumption and thyroid cancer are both increasing, our study aimed to determine any possibl...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Navdeep, Singh Lubana, Sandeep, Arora, Saurabh, Sachmechi, Issac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430875/
https://www.ncbi.nlm.nih.gov/pubmed/32849937
http://dx.doi.org/10.14740/jocmr4258
_version_ 1783571499480776704
author Singh, Navdeep
Singh Lubana, Sandeep
Arora, Saurabh
Sachmechi, Issac
author_facet Singh, Navdeep
Singh Lubana, Sandeep
Arora, Saurabh
Sachmechi, Issac
author_sort Singh, Navdeep
collection PubMed
description BACKGROUND: In recent decades, data from certain observational studies have stirred controversy over artificial sweeteners by linking them with certain malignancies. As the incidences of artificial sweetener consumption and thyroid cancer are both increasing, our study aimed to determine any possible association between them. METHODS: This retrospective observational study enrolled 50 patients (group 1) with proven diagnosis of well-differentiated thyroid cancer (WDTC) and 50 control subjects (group 2) diagnosed as having benign thyroid nodule by fine-needle aspiration. The survey questionnaire included the total amount and duration of intake of artificial sweeteners. RESULTS: Increased consumption of artificial sweeteners was noted in group 1 as compared to group 2, which was statistically significant (76% vs. 24%, P < 0.01). This study suggested that the use of an average of four packets (4 g) per day of artificial sweetener for an average duration of 5 years is associated with WDTC. CONCLUSIONS: Our study emphasizes the significance of artificial sweetener consumption as a potential risk factor for WDTC and increase in public awareness regarding this association if other studies in future report similar findings.
format Online
Article
Text
id pubmed-7430875
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elmer Press
record_format MEDLINE/PubMed
spelling pubmed-74308752020-08-25 A Study of Artificial Sweeteners and Thyroid Cancer Risk Singh, Navdeep Singh Lubana, Sandeep Arora, Saurabh Sachmechi, Issac J Clin Med Res Original Article BACKGROUND: In recent decades, data from certain observational studies have stirred controversy over artificial sweeteners by linking them with certain malignancies. As the incidences of artificial sweetener consumption and thyroid cancer are both increasing, our study aimed to determine any possible association between them. METHODS: This retrospective observational study enrolled 50 patients (group 1) with proven diagnosis of well-differentiated thyroid cancer (WDTC) and 50 control subjects (group 2) diagnosed as having benign thyroid nodule by fine-needle aspiration. The survey questionnaire included the total amount and duration of intake of artificial sweeteners. RESULTS: Increased consumption of artificial sweeteners was noted in group 1 as compared to group 2, which was statistically significant (76% vs. 24%, P < 0.01). This study suggested that the use of an average of four packets (4 g) per day of artificial sweetener for an average duration of 5 years is associated with WDTC. CONCLUSIONS: Our study emphasizes the significance of artificial sweetener consumption as a potential risk factor for WDTC and increase in public awareness regarding this association if other studies in future report similar findings. Elmer Press 2020-08 2020-07-01 /pmc/articles/PMC7430875/ /pubmed/32849937 http://dx.doi.org/10.14740/jocmr4258 Text en Copyright 2020, Singh et al. http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Singh, Navdeep
Singh Lubana, Sandeep
Arora, Saurabh
Sachmechi, Issac
A Study of Artificial Sweeteners and Thyroid Cancer Risk
title A Study of Artificial Sweeteners and Thyroid Cancer Risk
title_full A Study of Artificial Sweeteners and Thyroid Cancer Risk
title_fullStr A Study of Artificial Sweeteners and Thyroid Cancer Risk
title_full_unstemmed A Study of Artificial Sweeteners and Thyroid Cancer Risk
title_short A Study of Artificial Sweeteners and Thyroid Cancer Risk
title_sort study of artificial sweeteners and thyroid cancer risk
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430875/
https://www.ncbi.nlm.nih.gov/pubmed/32849937
http://dx.doi.org/10.14740/jocmr4258
work_keys_str_mv AT singhnavdeep astudyofartificialsweetenersandthyroidcancerrisk
AT singhlubanasandeep astudyofartificialsweetenersandthyroidcancerrisk
AT arorasaurabh astudyofartificialsweetenersandthyroidcancerrisk
AT sachmechiissac astudyofartificialsweetenersandthyroidcancerrisk
AT singhnavdeep studyofartificialsweetenersandthyroidcancerrisk
AT singhlubanasandeep studyofartificialsweetenersandthyroidcancerrisk
AT arorasaurabh studyofartificialsweetenersandthyroidcancerrisk
AT sachmechiissac studyofartificialsweetenersandthyroidcancerrisk