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Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines

BACKGROUND: Statins are widely prescribed to lower plasma low-density lipoprotein cholesterol levels. Though statins reduce cardiovascular disease risk overall, statin efficacy varies, and some people experience adverse side effects while on statin treatment. Statins also have pleiotropic effects no...

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Detalles Bibliográficos
Autores principales:	Theusch, Elizabeth, Chen, Yii-Der I., Rotter, Jerome I., Krauss, Ronald M., Medina, Marisa W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430882/ https://www.ncbi.nlm.nih.gov/pubmed/32787775 http://dx.doi.org/10.1186/s12864-020-06966-4

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