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Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme

The 5′ messenger RNA (mRNA) cap structure enhances translation and protects the transcript against exonucleolytic degradation. During mRNA turnover, this cap is removed from the mRNA. This decapping step is catalyzed by the Scavenger Decapping Enzyme (DcpS), in case the mRNA has been exonucleolyticl...

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Detalles Bibliográficos
Autores principales: Fuchs, Anna-Lisa, Wurm, Jan Philip, Neu, Ancilla, Sprangers, Remco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431086/
https://www.ncbi.nlm.nih.gov/pubmed/32723815
http://dx.doi.org/10.1073/pnas.2009362117

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