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Sensitization of knee-innervating sensory neurons by tumor necrosis factor-α-activated fibroblast-like synoviocytes: an in vitro, coculture model of inflammatory pain
Pain is a principal contributor to the global burden of arthritis with peripheral sensitization being a major cause of arthritis-related pain. Within the knee joint, distal endings of dorsal root ganglion neurons (knee neurons) interact with fibroblast-like synoviocytes (FLS) and the inflammatory me...
Autores principales: | Chakrabarti, Sampurna, Hore, Zoe, Pattison, Luke A., Lalnunhlimi, Sylvine, Bhebhe, Charity N., Callejo, Gerard, Bulmer, David C., Taams, Leonie S., Denk, Franziska, Smith, Ewan St. John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431145/ https://www.ncbi.nlm.nih.gov/pubmed/32332252 http://dx.doi.org/10.1097/j.pain.0000000000001890 |
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