Massive Acetaminophen Overdose

The authors present a case of a fatal intentional acetaminophen (APAP) overdose and remind the physician how ubiquitous the drug is. This case presentation highlights the clinical presentation and treatment options for APAP overdose in unresponsive patients. In cases of massive APAP overdose (> 3...

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Detalles Bibliográficos
Autores principales: Stead, Thor S, Jeong, Jae Yun, Ganti, Latha, Rubero, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Emergency Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431296/
https://www.ncbi.nlm.nih.gov/pubmed/32821608
http://dx.doi.org/10.7759/cureus.9262
Descripción
Sumario:The authors present a case of a fatal intentional acetaminophen (APAP) overdose and remind the physician how ubiquitous the drug is. This case presentation highlights the clinical presentation and treatment options for APAP overdose in unresponsive patients. In cases of massive APAP overdose (> 300 µg/ml plasma at four hours post-ingestion), prompt administration of N-acetylcysteine (NAC) and early hemodialysis are indicated.

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