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(177)Lu radiolabeling and preclinical theranostic study of 1C1m-Fc: an anti-TEM-1 scFv-Fc fusion protein in soft tissue sarcoma

PURPOSE: TEM-1 (tumor endothelial marker-1) is a single-pass transmembrane cell surface glycoprotein expressed at high levels by tumor vasculature and malignant cells. We aimed to perform a preclinical investigation of a novel anti-TEM-1 scFv-Fc fusion antibody, 1C1m-Fc, which was radiolabeled with...

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Detalles Bibliográficos
Autores principales:	Delage, J. A., Faivre-Chauvet, A., Fierle, J. K., Gnesin, S., Schaefer, N., Coukos, G., Dunn, S. M., Viertl, D., Prior, J. O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431510/ https://www.ncbi.nlm.nih.gov/pubmed/32804276 http://dx.doi.org/10.1186/s13550-020-00685-3

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