Farnesoid X receptor antagonizes Wnt/β-catenin signaling in colorectal tumorigenesis

Farnesoid X receptor (FXR, encoded by NR1H4), a critical regulator of bile acid homeostasis, is widely implicated in human tumorigenesis. However, the functional role of FXR in colorectal cancer (CRC) and the precise molecular mechanism remain unclear. In this study, we demonstrated that FXR express...

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Detalles Bibliográficos
Autores principales: Yu, Junhui, Li, Shan, Guo, Jing, Xu, Zhengshui, Zheng, Jianbao, Sun, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431544/
https://www.ncbi.nlm.nih.gov/pubmed/32807788
http://dx.doi.org/10.1038/s41419-020-02819-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431544/
https://www.ncbi.nlm.nih.gov/pubmed/32807788
http://dx.doi.org/10.1038/s41419-020-02819-w

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