Cargando…

NY-ESO-1 Protein Vaccine Combining Alum, CpG ODN, and HH2 Complex Adjuvant Induces Protective and Therapeutic Anti-Tumor Responses in Murine Multiple Myeloma

BACKGROUND: NY-ESO-1 is an ideal target for multiple myeloma immunotherapy. Alum, CpG ODN and HH2 complex is a safe and effective adjuvant for cancer vaccine. METHODS: We constructed NY-ESO-1 protein vaccine combined with alum, CpG ODN, and HH2 complex adjuvant to immunize the BALB/c mice inoculated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Hao, Huang, Wei, Gao, Hua, Liu, Ting Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431605/ https://www.ncbi.nlm.nih.gov/pubmed/32884292 http://dx.doi.org/10.2147/OTT.S255713

Ejemplares similares

The novel complex combination of alum, CpG ODN and HH2 as adjuvant in cancer vaccine effectively suppresses tumor growth in vivo
por: Tian, Yaomei, et al.
Publicado: (2017)

CpG-ODN Shapes Alum Adjuvant Activity Signaling via MyD88 and IL-10
por: Mirotti, Luciana, et al.
Publicado: (2017)

Effective inhibition of melanoma tumorigenesis and growth via a new complex vaccine based on NY-ESO-1-alum-polysaccharide-HH2
por: Li, Meng, et al.
Publicado: (2014)

Forging a potent vaccine adjuvant: CpG ODN/cationic peptide nanorings
por: Gungor, Bilgi, et al.
Publicado: (2014)

Characteristic of K3 (CpG-ODN) as a Transcutaneous Vaccine Formulation Adjuvant
por: Ito, Sayami, et al.
Publicado: (2020)

Comparison of in vivo Adjuvanticity of Liposomal PO CpG ODN with Liposomal PS CpG ODN: Soluble Leishmania Antigens as a Model
por: Golali, Ensieh, et al.
Publicado: (2012)

The effect of CpG-ODN on antigen presenting cells of the foal
por: Flaminio, M Julia BF, et al.
Publicado: (2007)

CpG ODN and ISCOMATRIX Adjuvant: A Synergistic Adjuvant Combination Inducing Strong T-Cell IFN-γ Responses
por: McCluskie, Michael J., et al.
Publicado: (2013)

Effect of CpG ODN on monocytic myeloid derived suppressor cells
por: Shirota, Hidekazu, et al.
Publicado: (2012)

TRAIL is involved in CpG ODN-mediated anti-apoptotic signals
por: LIM, EUN-JUNG, et al.
Publicado: (2011)

Immunogenicity evaluation of the HIV-1 Tat containing polyepitope DNA vaccine adjuvanted with CpG-ODNs in mice
por: Ollah Jazaeri, Ehsan, et al.
Publicado: (2021)

Alum/CpG Adjuvanted Inactivated COVID-19 Vaccine with Protective Efficacy against SARS-CoV-2 and Variants
por: Zhang, Yuntao, et al.
Publicado: (2022)

Immunotherapy with CpG-ODN in neoplastic meningitis: A phase I trial
por: Ursu, Renata, et al.
Publicado: (2015)

CpG-ODN and MPLA Prevent Mortality in a Murine Model of Post-Hemorrhage-Staphyloccocus aureus Pneumonia
por: Roquilly, Antoine, et al.
Publicado: (2010)

Limited Effect of CpG ODN in Preventing Type 1 Diabetes in NOD Mice
por: Lee, Byong Jun, et al.
Publicado: (2005)

Toll-like receptor 9 interaction with CpG ODN – An in silico analysis approach
por: Zhou, Wei, et al.
Publicado: (2013)

Identification of Differentially Expressed lncRNAs in a CpG ODN-Activated Macrophage
por: Zheng, Ying, et al.
Publicado: (2020)

Development of recombinant COVID-19 vaccine based on CHO-produced, prefusion spike trimer and alum/CpG adjuvants
por: Liu, Haitao, et al.
Publicado: (2021)

A plasmid containing CpG ODN as vaccine adjuvant against grass carp reovirus in grass carp Ctenopharyngodon idella
por: Su, Hang, et al.
Publicado: (2017)

Evaluation of CpG-ODN-Adjuvanted Toxoplasma gondii Virus-Like Particle Vaccine upon One, Two, and Three Immunizations
por: Kang, Hae-Ji, et al.
Publicado: (2020)

The Role of Liposomal CpG ODN on the Course of L. major Infection in BALB/C Mice
por: Hejazi, H, et al.
Publicado: (2010)

Increased Sensitivity to Chemotherapy Induced by CpG-ODN Treatment Is Mediated by microRNA Modulation
por: De Cecco, Loris, et al.
Publicado: (2013)

CpG-ODN Class C Mediated Immunostimulation in Rabbit Model of Trypanosoma evansi Infection
por: Kumar, Parveen, et al.
Publicado: (2015)

Pleiotropic action of CpG-ODN on endothelium and macrophages attenuates angiogenesis through distinct pathways
por: Wu, Jiahui, et al.
Publicado: (2016)

Radiosensitization by CpG ODN7909 in an epidermoid laryngeal carcinoma Hep-2 cell line
por: Wang, Shu, et al.
Publicado: (2017)

Treatment with phosphodiester CpG-ODN ameliorates atopic dermatitis by enhancing TGF-β signaling
por: Ham, Won-Kook, et al.
Publicado: (2021)

CpG-Containing Oligodeoxynucleotides and Freund Adjuvant in Combination with Alum Augment the Production of Monoclonal Antibodies Against Recombinant HBsAg
por: Khayyati Kohnehshahri, Mahsa, et al.
Publicado: (2022)

Evaluation of Leishmanization Using Iranian Lizard Leishmania Mixed With CpG-ODN as a Candidate Vaccine Against Experimental Murine Leishmaniasis
por: Keshavarzian, Nafiseh, et al.
Publicado: (2020)

CpG oligodeoxynucleotides as mucosal adjuvants
por: Iho, Sumiko, et al.
Publicado: (2015)

TLR9-mediated ARF6 activation is involved in advancing CpG ODN cellular uptake
por: Wu, Jing-Yiing, et al.
Publicado: (2012)

High efficacy of CpG-ODN, Cetuximab and Cisplatin combination for very advanced ovarian xenograft tumors
por: Sommariva, Michele, et al.
Publicado: (2013)

Preparation and characterization of PLGA nanospheres loaded with inactivated influenza virus, CpG-ODN and Quillaja saponin
por: Mohajer, Maryam, et al.
Publicado: (2014)

In Ovo Administration of CpG ODN Induces Expression of Immune Response Genes in Neonatal Chicken Spleen
por: Sajewicz-Krukowska, Joanna, et al.
Publicado: (2017)

Synthetic CpG-ODN rapidly enriches immune compartments in neonatal chicks to induce protective immunity against bacterial infections
por: Gunawardana, Thushari, et al.
Publicado: (2019)

The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8(+) T-cell responses in vitro
por: Papagno, Laura, et al.
Publicado: (2020)

LNP-CpG ODN-adjuvanted varicella-zoster virus glycoprotein E induced comparable levels of immunity with Shingrix™ in VZV-primed mice
por: Luan, Ning, et al.
Publicado: (2022)

CpG immunostimulatory oligodeoxynucleotide 1826 as a novel nasal ODN adjuvant enhanced the protective efficacy of the periodontitis gene vaccine in a periodontitis model in SD rats
por: Bai, Guohui, et al.
Publicado: (2021)

Use of thermolytic protective groups to prevent G-tetrad formation in CpG ODN type D: structural studies and immunomodulatory activity in primates
por: Puig, Montserrat, et al.
Publicado: (2006)

Allergen-Specific Immunotherapy With Liposome Containing CpG-ODN in Murine Model of Asthma Relies on MyD88 Signaling in Dendritic Cells
por: Alberca-Custodio, Ricardo Wesley, et al.
Publicado: (2020)

CpG ODN1826 as a Promising Mucin1-Maltose-Binding Protein Vaccine Adjuvant Induced DC Maturation and Enhanced Antitumor Immunity
por: Jie, Jing, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_f00klk8d17817e1tte0vc7fbk1