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The Long-term Visual Outcomes of Primary Congenital Glaucoma
PURPOSE: To evaluate the long-term visual outcomes of ab externo trabeculotomy for primary congenital glaucoma (PCG) at a single pediatric ophthalmology center. METHODS: In this retrospective single-center case series, data from 63 eyes of 40 patients who underwent ab externo trabeculotomy between S...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PUBLISHED BY KNOWLEDGE E
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431714/ https://www.ncbi.nlm.nih.gov/pubmed/32864063 http://dx.doi.org/10.18502/jovr.v15i3.7451 |
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author | Esfandiari, Hamed Prager, Alisa Hassanpour, Kiana Kurup, Sudhi P. Mets-Halgrimson, Rebecca Yoon, Hawke Zeid, Janice Lasky Mets, Marilyn B. Rahmani, Bahram |
author_facet | Esfandiari, Hamed Prager, Alisa Hassanpour, Kiana Kurup, Sudhi P. Mets-Halgrimson, Rebecca Yoon, Hawke Zeid, Janice Lasky Mets, Marilyn B. Rahmani, Bahram |
author_sort | Esfandiari, Hamed |
collection | PubMed |
description | PURPOSE: To evaluate the long-term visual outcomes of ab externo trabeculotomy for primary congenital glaucoma (PCG) at a single pediatric ophthalmology center. METHODS: In this retrospective single-center case series, data from 63 eyes of 40 patients who underwent ab externo trabeculotomy between September 2006 and June 2018 were included. The data were analyzed for best corrected visual acuity (BCVA), stereopsis, and surgical success. Kaplan–Meier analysis was performed using the surgical success criteria defined as intraocular pressure (IOP) [Formula: see text] 21 mmHg and [Formula: see text] 20% below baseline without the need for additional glaucoma surgery. RESULTS: BCVA at the time of diagnosis was 0.37 [Formula: see text] 0.48 logMAR, which changed to 0.51 [Formula: see text] 0.56 logMAR at the final follow-up (P = 0.08). Twenty-five percent of patients had BCVA equal to or better than 20/40 at the final visit. The mean refraction at baseline was –4.78 [Formula: see text] 5.87 diopters, which changed to less myopic refraction of –2.90 [Formula: see text] 3.83 diopters at the final visit. Optical correction was prescribed in 66% of eyes at the final visit. The average final stereopsis was 395.33 sec of arc. The linear regression model showed a significant association between the surgery success rate and final BCVA as well as stereoacuity (P-values: 0.04 and 0.03, respectively). Intraocular pressure (IOP) decreased significantly from 29.79 [Formula: see text] 7.67 mmHg at baseline to 16.13 [Formula: see text] 3.41 mmHg at the final follow-up (P = 0.001). CONCLUSION: Patients with PCG can achieve an acceptable visual acuity and stereoacuity, particularly in cases of timely intervention and close follow-up. |
format | Online Article Text |
id | pubmed-7431714 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | PUBLISHED BY KNOWLEDGE E |
record_format | MEDLINE/PubMed |
spelling | pubmed-74317142020-08-28 The Long-term Visual Outcomes of Primary Congenital Glaucoma Esfandiari, Hamed Prager, Alisa Hassanpour, Kiana Kurup, Sudhi P. Mets-Halgrimson, Rebecca Yoon, Hawke Zeid, Janice Lasky Mets, Marilyn B. Rahmani, Bahram J Ophthalmic Vis Res Original Article PURPOSE: To evaluate the long-term visual outcomes of ab externo trabeculotomy for primary congenital glaucoma (PCG) at a single pediatric ophthalmology center. METHODS: In this retrospective single-center case series, data from 63 eyes of 40 patients who underwent ab externo trabeculotomy between September 2006 and June 2018 were included. The data were analyzed for best corrected visual acuity (BCVA), stereopsis, and surgical success. Kaplan–Meier analysis was performed using the surgical success criteria defined as intraocular pressure (IOP) [Formula: see text] 21 mmHg and [Formula: see text] 20% below baseline without the need for additional glaucoma surgery. RESULTS: BCVA at the time of diagnosis was 0.37 [Formula: see text] 0.48 logMAR, which changed to 0.51 [Formula: see text] 0.56 logMAR at the final follow-up (P = 0.08). Twenty-five percent of patients had BCVA equal to or better than 20/40 at the final visit. The mean refraction at baseline was –4.78 [Formula: see text] 5.87 diopters, which changed to less myopic refraction of –2.90 [Formula: see text] 3.83 diopters at the final visit. Optical correction was prescribed in 66% of eyes at the final visit. The average final stereopsis was 395.33 sec of arc. The linear regression model showed a significant association between the surgery success rate and final BCVA as well as stereoacuity (P-values: 0.04 and 0.03, respectively). Intraocular pressure (IOP) decreased significantly from 29.79 [Formula: see text] 7.67 mmHg at baseline to 16.13 [Formula: see text] 3.41 mmHg at the final follow-up (P = 0.001). CONCLUSION: Patients with PCG can achieve an acceptable visual acuity and stereoacuity, particularly in cases of timely intervention and close follow-up. PUBLISHED BY KNOWLEDGE E 2020-07-29 /pmc/articles/PMC7431714/ /pubmed/32864063 http://dx.doi.org/10.18502/jovr.v15i3.7451 Text en Copyright © 2020 Esfandiari et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Original Article Esfandiari, Hamed Prager, Alisa Hassanpour, Kiana Kurup, Sudhi P. Mets-Halgrimson, Rebecca Yoon, Hawke Zeid, Janice Lasky Mets, Marilyn B. Rahmani, Bahram The Long-term Visual Outcomes of Primary Congenital Glaucoma |
title | The Long-term Visual Outcomes of Primary Congenital Glaucoma |
title_full | The Long-term Visual Outcomes of Primary Congenital Glaucoma |
title_fullStr | The Long-term Visual Outcomes of Primary Congenital Glaucoma |
title_full_unstemmed | The Long-term Visual Outcomes of Primary Congenital Glaucoma |
title_short | The Long-term Visual Outcomes of Primary Congenital Glaucoma |
title_sort | long-term visual outcomes of primary congenital glaucoma |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431714/ https://www.ncbi.nlm.nih.gov/pubmed/32864063 http://dx.doi.org/10.18502/jovr.v15i3.7451 |
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