Controlling the stereochemistry in 2-oxo-aldehyde-derived Ugi adducts through the cinchona alkaloid-promoted electrophilic fluorination

In this report, we introduce a new strategy for controlling the stereochemistry in Ugi adducts. Instead of controlling stereochemistry directly during the Ugi reaction we have attempted to stereodefine the chiral center at the peptidyl position through the post-Ugi functionalization. In order to ach...

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Detalles Bibliográficos
Autores principales: Wang, Yuqing, Wang, Gaigai, Peshkov, Anatoly A, Yao, Ruwei, Hasan, Muhammad, Zaman, Manzoor, Liu, Chao, Kashtanov, Stepan, Pereshivko, Olga P, Peshkov, Vsevolod A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431756/
https://www.ncbi.nlm.nih.gov/pubmed/32831953
http://dx.doi.org/10.3762/bjoc.16.163

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