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Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages

Japanese encephalitis virus (JEV) is a flavivirus that causes Japanese encephalitis (JE), which has an unclear pathogenesis. Despite vaccination, thousands of deaths attributed to JE are reported annually. In this study, we report that mice deficient for Axl, a receptor tyrosine kinase that plays mu...

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Detalles Bibliográficos
Autores principales:	Wang, Zhao-Yang, Zhen, Zi-Da, Fan, Dong-Ying, Qin, Cheng-Feng, Han, Dai-Shu, Zhou, Hong-Ning, Wang, Pei-Gang, An, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431807/ https://www.ncbi.nlm.nih.gov/pubmed/32611752 http://dx.doi.org/10.1128/JVI.00602-20

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