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Aging is associated with a decline in Atg9b‐mediated autophagosome formation and appearance of enlarged mitochondria in the heart

Advancing age is a major risk factor for developing heart disease, and the biological processes contributing to aging are currently under intense investigation. Autophagy is an important cellular quality control mechanism that is reduced in tissues with age but the molecular mechanisms underlying th...

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Detalles Bibliográficos
Autores principales: Liang, Wenjing, Moyzis, Alexandra G., Lampert, Mark A., Diao, Rachel Y., Najor, Rita H., Gustafsson, Åsa B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431832/
https://www.ncbi.nlm.nih.gov/pubmed/32627317
http://dx.doi.org/10.1111/acel.13187