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Aging is associated with a decline in Atg9b‐mediated autophagosome formation and appearance of enlarged mitochondria in the heart
Advancing age is a major risk factor for developing heart disease, and the biological processes contributing to aging are currently under intense investigation. Autophagy is an important cellular quality control mechanism that is reduced in tissues with age but the molecular mechanisms underlying th...
Autores principales: | Liang, Wenjing, Moyzis, Alexandra G., Lampert, Mark A., Diao, Rachel Y., Najor, Rita H., Gustafsson, Åsa B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431832/ https://www.ncbi.nlm.nih.gov/pubmed/32627317 http://dx.doi.org/10.1111/acel.13187 |
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